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Tytuł :
Retinoic acid enhances ovarian steroidogenesis by regulating granulosa cell proliferation and MESP2/STAR/CYP11A1 pathway.
Autorzy :
Cai S; State Key Laboratory of Animal Nutrition, China Agricultural University, Beijing 100193, PR China; Beijing Biofeed Additive Key Laboratory, China Agricultural University, Beijing 100193, PR China.
Chen M; State Key Laboratory of Animal Nutrition, China Agricultural University, Beijing 100193, PR China; Beijing Biofeed Additive Key Laboratory, China Agricultural University, Beijing 100193, PR China; Institute of Animal Husbandry and Veterinary Medicine, Beijing Academy of Agriculture and Forestry Sciences, Beijing 100097, PR China.
Xue B; State Key Laboratory of Animal Nutrition, China Agricultural University, Beijing 100193, PR China; Beijing Biofeed Additive Key Laboratory, China Agricultural University, Beijing 100193, PR China.
Zhu Z; State Key Laboratory of Animal Nutrition, China Agricultural University, Beijing 100193, PR China; Beijing Biofeed Additive Key Laboratory, China Agricultural University, Beijing 100193, PR China.
Wang X; State Key Laboratory of Animal Nutrition, China Agricultural University, Beijing 100193, PR China; Beijing Biofeed Additive Key Laboratory, China Agricultural University, Beijing 100193, PR China.
Li J; State Key Laboratory of Animal Nutrition, China Agricultural University, Beijing 100193, PR China.
Wang H; State Key Laboratory of Animal Nutrition, China Agricultural University, Beijing 100193, PR China; Beijing Biofeed Additive Key Laboratory, China Agricultural University, Beijing 100193, PR China.
Zeng X; State Key Laboratory of Animal Nutrition, China Agricultural University, Beijing 100193, PR China; Beijing Biofeed Additive Key Laboratory, China Agricultural University, Beijing 100193, PR China.
Qiao S; State Key Laboratory of Animal Nutrition, China Agricultural University, Beijing 100193, PR China; Beijing Biofeed Additive Key Laboratory, China Agricultural University, Beijing 100193, PR China.
Zeng X; State Key Laboratory of Animal Nutrition, China Agricultural University, Beijing 100193, PR China; Beijing Biofeed Additive Key Laboratory, China Agricultural University, Beijing 100193, PR China. Electronic address: .
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Źródło :
Journal of advanced research [J Adv Res] 2024 Apr; Vol. 58, pp. 163-173. Date of Electronic Publication: 2023 Jun 13.
Typ publikacji :
Journal Article
MeSH Terms :
Ovary*/metabolism
Cholesterol Side-Chain Cleavage Enzyme*
Female ; Swine ; Animals ; Pregnancy ; Humans ; Tretinoin ; Phosphatidylinositol 3-Kinases ; Vitamin A ; Hedgehog Proteins ; Progesterone ; Cell Proliferation ; Mammals/metabolism ; Basic Helix-Loop-Helix Transcription Factors
Czasopismo naukowe
Tytuł :
The multistep oxidation of cholesterol to pregnenolone by human cytochrome P450 11A1 is highly processive.
Autorzy :
McCarty KD; Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.
Liu L; Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.
Tateishi Y; Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.
Wapshott-Stehli HL; Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.
Guengerich FP; Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, Tennessee, USA. Electronic address: .
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Źródło :
The Journal of biological chemistry [J Biol Chem] 2024 Jan; Vol. 300 (1), pp. 105495. Date of Electronic Publication: 2023 Nov 24.
Typ publikacji :
Journal Article
MeSH Terms :
Cholesterol*/chemistry
Cholesterol*/metabolism
Cholesterol Side-Chain Cleavage Enzyme*/chemistry
Cholesterol Side-Chain Cleavage Enzyme*/isolation & purification
Cholesterol Side-Chain Cleavage Enzyme*/metabolism
Pregnenolone*/chemistry
Pregnenolone*/metabolism
Humans ; Adrenodoxin/metabolism ; Kinetics ; Protein Binding ; Oxidation-Reduction ; Molecular Structure
Czasopismo naukowe
Tytuł :
Differential tissue expression of sex steroid-synthesizing enzyme CYP11A1 in male Tibetan sheep ( Ovis aries ).
Autorzy :
Wang H; College of Animal Science and Technology, Gansu Agricultural University, Lanzhou, China.; Gansu Key Laboratory of Animal Generational Physiology and Reproductive Regulation, Gansu Agricultural University, Lanzhou, China.
Wang X; College of Animal Science and Technology, Gansu Agricultural University, Lanzhou, China.; Gansu Key Laboratory of Animal Generational Physiology and Reproductive Regulation, Gansu Agricultural University, Lanzhou, China.
Li T; College of Animal Science and Technology, Gansu Agricultural University, Lanzhou, China.; Gansu Key Laboratory of Animal Generational Physiology and Reproductive Regulation, Gansu Agricultural University, Lanzhou, China.
An X; College of Animal Science and Technology, Gansu Agricultural University, Lanzhou, China.; Gansu Key Laboratory of Animal Generational Physiology and Reproductive Regulation, Gansu Agricultural University, Lanzhou, China.
Chen N; College of Animal Science and Technology, Gansu Agricultural University, Lanzhou, China.; Gansu Key Laboratory of Animal Generational Physiology and Reproductive Regulation, Gansu Agricultural University, Lanzhou, China.
Shi H; College of Animal Science and Technology, Gansu Agricultural University, Lanzhou, China.; Gansu Key Laboratory of Animal Generational Physiology and Reproductive Regulation, Gansu Agricultural University, Lanzhou, China.
Su M; Gansu Key Laboratory of Animal Generational Physiology and Reproductive Regulation, Gansu Agricultural University, Lanzhou, China.
Ma K; College of Animal Science and Technology, Gansu Agricultural University, Lanzhou, China.; Gansu Key Laboratory of Animal Generational Physiology and Reproductive Regulation, Gansu Agricultural University, Lanzhou, China.
Hao Z; College of Animal Science and Technology, Gansu Agricultural University, Lanzhou, China.; Gansu Key Laboratory of Animal Generational Physiology and Reproductive Regulation, Gansu Agricultural University, Lanzhou, China.
Duan X; Nongfayuan (Zhejiang) Agricultural Development Co., Ltd., Huzhou, Zhejiang, China.
Ma Y; College of Animal Science and Technology, Gansu Agricultural University, Lanzhou, China.; Gansu Key Laboratory of Animal Generational Physiology and Reproductive Regulation, Gansu Agricultural University, Lanzhou, China.; Sheep Breeding Biotechnology Engineering Laboratory of Gansu Province, Minqin, China.
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Źródło :
Animal biotechnology [Anim Biotechnol] 2023 Dec; Vol. 34 (7), pp. 2900-2909. Date of Electronic Publication: 2022 Sep 28.
Typ publikacji :
Journal Article
MeSH Terms :
Sheep, Domestic*
Cholesterol Side-Chain Cleavage Enzyme*/genetics
Cholesterol Side-Chain Cleavage Enzyme*/metabolism
Sheep/genetics ; Male ; Animals ; Tibet ; Testis/metabolism ; Steroids/metabolism
Czasopismo naukowe
Tytuł :
Perfluorooctanoic acid (PFOA) inhibits steroidogenesis and mitochondrial function in bovine granulosa cells in vitro.
Autorzy :
Kabakci R; Department of Physiology, Faculty of Veterinary Medicine, Kirikkale University, 71450 Yahsihan, Kirikkale, Turkey; Deparment of Obstetrics and Gynecology, University of Nebraska Medical Center, Omaha, NE 68198, USA.
Clark KL; Deparment of Obstetrics and Gynecology, University of Nebraska Medical Center, Omaha, NE 68198, USA; Veterans Affairs Nebraska-Western Iowa Health Care System, Omaha, NE 68105, USA.
Plewes MR; Deparment of Obstetrics and Gynecology, University of Nebraska Medical Center, Omaha, NE 68198, USA; Deparment of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE 68198, USA; Veterans Affairs Nebraska-Western Iowa Health Care System, Omaha, NE 68105, USA.
Monaco CF; Deparment of Obstetrics and Gynecology, University of Nebraska Medical Center, Omaha, NE 68198, USA; Department of Cellular and Integrative Physiology, University of Nebraska Medical Center, Nebraska Medical Center, Omaha, NE 68198, USA.
Davis JS; Deparment of Obstetrics and Gynecology, University of Nebraska Medical Center, Omaha, NE 68198, USA; Deparment of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE 68198, USA; Veterans Affairs Nebraska-Western Iowa Health Care System, Omaha, NE 68105, USA. Electronic address: .
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Źródło :
Environmental pollution (Barking, Essex : 1987) [Environ Pollut] 2023 Dec 01; Vol. 338, pp. 122698. Date of Electronic Publication: 2023 Oct 11.
Typ publikacji :
Journal Article
MeSH Terms :
Cholesterol Side-Chain Cleavage Enzyme*/genetics
Cholesterol Side-Chain Cleavage Enzyme*/metabolism
Caprylates*/toxicity
Caprylates*/metabolism
Female ; Humans ; Animals ; Cattle ; Granulosa Cells ; Mitochondria
Czasopismo naukowe
Tytuł :
BMAL1 positively correlates with genes regulating steroidogenesis in human luteinized granulosa cells.
Autorzy :
Kawamura T; Department of Obstetrics and Gynecology, Tokyo Medical University, Tokyo, Japan.
Dai Y; Department of Obstetrics and Gynecology, Tokyo Medical University, Tokyo, Japan.
Ono M; Department of Obstetrics and Gynecology, Tokyo Medical University, Tokyo, Japan.
Kikuchi T; Department of Obstetrics and Gynecology, Tokyo Medical University, Tokyo, Japan.
Yamanaka A; Department of Obstetrics and Gynecology, Tokyo Medical University, Tokyo, Japan.
Ueno K; Department of Obstetrics and Gynecology, Tokyo Medical University, Tokyo, Japan.
Kojima J; Department of Obstetrics and Gynecology, Tokyo Medical University, Tokyo, Japan.
Fujiwara T; Department of Social Work and Life Design, Kyoto Notre Dame University, Kyoto, Japan.
Daikoku T; Division of Animal Disease Model, Research Center for Experimental Modeling of Human Disease, Graduate School of Medical Science, Kanazawa University, Kanazawa, Japan.
Maida Y; Department of Nursing, College of Medical, Pharmaceutical, and Health Sciences, Kanazawa University, Kanazawa, Japan.
Ando H; Department of Cellular and Molecular Function Analysis, Graduate School of Medical Science, Kanazawa University, Kanazawa, Japan.
Fujiwara H; Department of Obstetrics and Gynecology, Graduate School of Medical Science, Kanazawa University, Kanazawa, Japan.
Kuji N; Department of Obstetrics and Gynecology, Tokyo Medical University, Tokyo, Japan.
Nishi H; Department of Obstetrics and Gynecology, Tokyo Medical University, Tokyo, Japan.
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Źródło :
Reproduction (Cambridge, England) [Reproduction] 2024 Jan 23; Vol. 167 (2). Date of Electronic Publication: 2024 Jan 23 (Print Publication: 2024).
Typ publikacji :
Journal Article
MeSH Terms :
ARNTL Transcription Factors*/genetics
Cholesterol Side-Chain Cleavage Enzyme*/metabolism
Female ; Humans ; Estradiol/metabolism ; Granulosa Cells/metabolism ; Progesterone/metabolism
Czasopismo naukowe
Tytuł :
Expression and regulation of Noggin4 gene in chicken ovarian follicles and its role in the proliferation and differentiation of granulosa cells.
Autorzy :
Gong Y; Shandong Provincial Key Laboratory of Animal Biotechnology and Disease Control and Prevention, College of Animal Science and Veterinary Medicine, Shandong Agricultural University, Tai'an, 271018, China.
Li D; Shandong Provincial Key Laboratory of Animal Biotechnology and Disease Control and Prevention, College of Animal Science and Veterinary Medicine, Shandong Agricultural University, Tai'an, 271018, China.
Sun Y; Shandong Provincial Key Laboratory of Animal Biotechnology and Disease Control and Prevention, College of Animal Science and Veterinary Medicine, Shandong Agricultural University, Tai'an, 271018, China.
Kang L; Shandong Provincial Key Laboratory of Animal Biotechnology and Disease Control and Prevention, College of Animal Science and Veterinary Medicine, Shandong Agricultural University, Tai'an, 271018, China.
Jiang Y; Shandong Provincial Key Laboratory of Animal Biotechnology and Disease Control and Prevention, College of Animal Science and Veterinary Medicine, Shandong Agricultural University, Tai'an, 271018, China. Electronic address: .
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Źródło :
Theriogenology [Theriogenology] 2023 Dec; Vol. 212, pp. 83-90. Date of Electronic Publication: 2023 Sep 09.
Typ publikacji :
Journal Article
MeSH Terms :
Chickens*/genetics
Chickens*/metabolism
Cholesterol Side-Chain Cleavage Enzyme*/metabolism
Female ; Animals ; Ovarian Follicle/physiology ; Granulosa Cells ; Cell Differentiation ; Gene Expression Regulation ; Follicle Stimulating Hormone/pharmacology ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Cell Proliferation
Czasopismo naukowe
Tytuł :
Resveratrol protects against high glucose-induced steroidogenesis and apoptosis in murine granulosa cells.
Autorzy :
Zhang N; Reproductive Medicine Center, Yantai Yuhuangding Hospital, Yantai, China. .
Shan Y; Reproductive Medicine Center, Yantai Yuhuangding Hospital, Yantai, China. .
Lian H; Reproductive Medicine Center, Yantai Yuhuangding Hospital, Yantai, China. .
Ma X; Reproductive Medicine Center, Yantai Yuhuangding Hospital, Yantai, China. .
Zhang W; Reproductive Medicine Center, Yantai Yuhuangding Hospital, Yantai, China. .
Liu X; Binzhou Medical University, Binzhou, China. .
Zhuang L; Reproductive Medicine Center, Yantai Yuhuangding Hospital, Yantai, China. .
Liu X; Reproductive Medicine Center, Yantai Yuhuangding Hospital, Yantai, China. .
Liu Y; Weifang Medical University, Weifang, China. .
Zheng K; Binzhou Medical University, Binzhou, China. .
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Źródło :
Cellular and molecular biology (Noisy-le-Grand, France) [Cell Mol Biol (Noisy-le-grand)] 2023 Nov 30; Vol. 69 (12), pp. 218-222. Date of Electronic Publication: 2023 Nov 30.
Typ publikacji :
Journal Article
MeSH Terms :
Progesterone*/pharmacology
Cholesterol Side-Chain Cleavage Enzyme*/metabolism
Female ; Mice ; Animals ; Resveratrol/pharmacology ; Caspase 3/metabolism ; Mice, Inbred C57BL ; Estradiol/pharmacology ; Follicle Stimulating Hormone/metabolism ; Granulosa Cells/metabolism ; Apoptosis ; Glucose/metabolism ; Cells, Cultured
Czasopismo naukowe
Tytuł :
Exploring the impact of CYP11A1's missense SNPs on the interaction between CYP11A1 and cholesterol: A comprehensive structural analysis and MD simulation study.
Autorzy :
Redouane S; Laboratory of Genomics and Human Genetics, Institut Pasteur du Maroc, Casablanca, Morocco; Laboratory of Physiopathology and Molecular Genetics, Department of Biology, Faculty of Sciences Ben M'Sik, Hassan II University, Casablanca, Morocco. Electronic address: .
Harmak H; Laboratory of Genomics and Human Genetics, Institut Pasteur du Maroc, Casablanca, Morocco.
Elkarhat Z; Laboratory of Genomics and Human Genetics, Institut Pasteur du Maroc, Casablanca, Morocco.
Charoute H; Research Unit of Epidemiology, Biostatistics and Bioinformatics, Institut Pasteur du Maroc, Casablanca, Morocco.
Malki A; Laboratory of Physiopathology and Molecular Genetics, Department of Biology, Faculty of Sciences Ben M'Sik, Hassan II University, Casablanca, Morocco.
Barakat A; Laboratory of Genomics and Human Genetics, Institut Pasteur du Maroc, Casablanca, Morocco.
Rouba H; Laboratory of Genomics and Human Genetics, Institut Pasteur du Maroc, Casablanca, Morocco.
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Źródło :
Computational biology and chemistry [Comput Biol Chem] 2023 Oct; Vol. 106, pp. 107937. Date of Electronic Publication: 2023 Aug 02.
Typ publikacji :
Journal Article
MeSH Terms :
Molecular Dynamics Simulation*
Cholesterol Side-Chain Cleavage Enzyme*/genetics
Cholesterol Side-Chain Cleavage Enzyme*/metabolism
Humans ; Polymorphism, Single Nucleotide ; Genome-Wide Association Study ; Steroids ; Cholesterol ; Hormones
Czasopismo naukowe
Tytuł :
Metabolism of Lumisterol 2 by CYP27A1.
Autorzy :
Wu D; School of Molecular Sciences, The University of Western Australia, Perth, WA 6009, Australia.
Nealon G; School of Molecular Sciences, The University of Western Australia, Perth, WA 6009, Australia; Centre for Microscopy, Characterisation and Analysis, The University of Western Australia, Perth, WA 6009, Australia.
Liu Y; School of Molecular Sciences, The University of Western Australia, Perth, WA 6009, Australia.
Kim TK; Department of Dermatology, University of Alabama at Birmingham, Birmingham, AL, USA.
Slominski AT; Department of Dermatology, University of Alabama at Birmingham, Birmingham, AL, USA; VA Medical Center, Birmingham, AL, USA.
Tuckey RC; School of Molecular Sciences, The University of Western Australia, Perth, WA 6009, Australia. Electronic address: .
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Źródło :
The Journal of steroid biochemistry and molecular biology [J Steroid Biochem Mol Biol] 2023 Oct; Vol. 233, pp. 106370. Date of Electronic Publication: 2023 Jul 25.
Typ publikacji :
Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
MeSH Terms :
Ergosterol*/metabolism
Cholesterol Side-Chain Cleavage Enzyme*/metabolism
Humans ; Hydroxylation ; Mass Spectrometry ; Ergocalciferols ; Cholestanetriol 26-Monooxygenase/metabolism
Czasopismo naukowe
Tytuł :
The role of platelet-derived growth factor BB signaling pathway in the regulation of stem and progenitor Leydig cell proliferation and steroidogenesis in male rats.
Autorzy :
Li X; Department of Anesthesiology and Perioperative Medicine, the Second Affiliated Hospital and Yuying Children's Hospital; Key Laboratory of Pediatric Anesthesiology, Ministry of Education; Key Laboratory of Anesthesiology of Zhejiang Province, Wenzhou Medical University, Wenzhou, Zhejiang 325027, China; Key Laboratory of Structural Malformations in Children of Zhejiang Province, Key Laboratory of Environment and Male Reproductive Medicine of Wenzhou, Wenzhou, Zhejiang Province 325000, China.
Quan H; Department of Anesthesiology and Perioperative Medicine, the Second Affiliated Hospital and Yuying Children's Hospital; Key Laboratory of Pediatric Anesthesiology, Ministry of Education; Key Laboratory of Anesthesiology of Zhejiang Province, Wenzhou Medical University, Wenzhou, Zhejiang 325027, China.
He J; Department of Anesthesiology and Perioperative Medicine, the Second Affiliated Hospital and Yuying Children's Hospital; Key Laboratory of Pediatric Anesthesiology, Ministry of Education; Key Laboratory of Anesthesiology of Zhejiang Province, Wenzhou Medical University, Wenzhou, Zhejiang 325027, China.
Li H; Department of Anesthesiology and Perioperative Medicine, the Second Affiliated Hospital and Yuying Children's Hospital; Key Laboratory of Pediatric Anesthesiology, Ministry of Education; Key Laboratory of Anesthesiology of Zhejiang Province, Wenzhou Medical University, Wenzhou, Zhejiang 325027, China; Key Laboratory of Structural Malformations in Children of Zhejiang Province, Key Laboratory of Environment and Male Reproductive Medicine of Wenzhou, Wenzhou, Zhejiang Province 325000, China.
Zhu Q; Department of Anesthesiology and Perioperative Medicine, the Second Affiliated Hospital and Yuying Children's Hospital; Key Laboratory of Pediatric Anesthesiology, Ministry of Education; Key Laboratory of Anesthesiology of Zhejiang Province, Wenzhou Medical University, Wenzhou, Zhejiang 325027, China.
Wang Y; Department of Anesthesiology and Perioperative Medicine, the Second Affiliated Hospital and Yuying Children's Hospital; Key Laboratory of Pediatric Anesthesiology, Ministry of Education; Key Laboratory of Anesthesiology of Zhejiang Province, Wenzhou Medical University, Wenzhou, Zhejiang 325027, China.
Zhu Y; Department of Anesthesiology and Perioperative Medicine, the Second Affiliated Hospital and Yuying Children's Hospital; Key Laboratory of Pediatric Anesthesiology, Ministry of Education; Key Laboratory of Anesthesiology of Zhejiang Province, Wenzhou Medical University, Wenzhou, Zhejiang 325027, China.
Ge RS; Department of Anesthesiology and Perioperative Medicine, the Second Affiliated Hospital and Yuying Children's Hospital; Key Laboratory of Pediatric Anesthesiology, Ministry of Education; Key Laboratory of Anesthesiology of Zhejiang Province, Wenzhou Medical University, Wenzhou, Zhejiang 325027, China; Key Laboratory of Structural Malformations in Children of Zhejiang Province, Key Laboratory of Environment and Male Reproductive Medicine of Wenzhou, Wenzhou, Zhejiang Province 325000, China. Electronic address: renshan_.
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Źródło :
The Journal of steroid biochemistry and molecular biology [J Steroid Biochem Mol Biol] 2023 Oct; Vol. 233, pp. 106344. Date of Electronic Publication: 2023 Jun 05.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cholesterol Side-Chain Cleavage Enzyme*/metabolism
Phosphatidylinositol 3-Kinases*/metabolism
Rats ; Male ; Animals ; Becaplermin/metabolism ; Becaplermin/pharmacology ; Rats, Sprague-Dawley ; Leydig Cells/metabolism ; Cell Proliferation ; Signal Transduction
Czasopismo naukowe
Tytuł :
Placental DNA methylation analysis of selective fetal growth restriction in monochorionic twins reveals aberrant methylated CYP11A1 gene for fetal growth restriction.
Autorzy :
Shi D; Shanghai Key Laboratory of Maternal Fetal Medicine, Shanghai Institute of Maternal-Fetal Medicine and Gynecologic Oncology, Department of Fetal Medicine & Prenatal Diagnosis Center, Shanghai First Maternity and Infant Hospital, School of Medicine, Tongji University, Shanghai, China.
Zhou X; Shanghai Key Laboratory of Maternal Fetal Medicine, Shanghai Institute of Maternal-Fetal Medicine and Gynecologic Oncology, Department of Fetal Medicine & Prenatal Diagnosis Center, Shanghai First Maternity and Infant Hospital, School of Medicine, Tongji University, Shanghai, China.
Cai L; Shanghai Key Laboratory of Maternal Fetal Medicine, Shanghai Institute of Maternal-Fetal Medicine and Gynecologic Oncology, Department of Fetal Medicine & Prenatal Diagnosis Center, Shanghai First Maternity and Infant Hospital, School of Medicine, Tongji University, Shanghai, China.
Wei X; Shanghai Key Laboratory of Maternal Fetal Medicine, Shanghai Institute of Maternal-Fetal Medicine and Gynecologic Oncology, Department of Fetal Medicine & Prenatal Diagnosis Center, Shanghai First Maternity and Infant Hospital, School of Medicine, Tongji University, Shanghai, China.
Zhang L; Shanghai Key Laboratory of Maternal Fetal Medicine, Shanghai Institute of Maternal-Fetal Medicine and Gynecologic Oncology, Department of Fetal Medicine & Prenatal Diagnosis Center, Shanghai First Maternity and Infant Hospital, School of Medicine, Tongji University, Shanghai, China.
Sun Q; Shanghai Key Laboratory of Maternal Fetal Medicine, Shanghai Institute of Maternal-Fetal Medicine and Gynecologic Oncology, Department of Fetal Medicine & Prenatal Diagnosis Center, Shanghai First Maternity and Infant Hospital, School of Medicine, Tongji University, Shanghai, China.
Zhou F; Shanghai Key Laboratory of Maternal Fetal Medicine, Shanghai Institute of Maternal-Fetal Medicine and Gynecologic Oncology, Department of Fetal Medicine & Prenatal Diagnosis Center, Shanghai First Maternity and Infant Hospital, School of Medicine, Tongji University, Shanghai, China.
Sun L; Shanghai Key Laboratory of Maternal Fetal Medicine, Shanghai Institute of Maternal-Fetal Medicine and Gynecologic Oncology, Department of Fetal Medicine & Prenatal Diagnosis Center, Shanghai First Maternity and Infant Hospital, School of Medicine, Tongji University, Shanghai, China.
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Źródło :
FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2023 Oct; Vol. 37 (10), pp. e23207.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cholesterol Side-Chain Cleavage Enzyme*
DNA Methylation*
Female ; Humans ; Pregnancy ; Placenta ; Fetal Growth Retardation/genetics ; Blotting, Western
Czasopismo naukowe
Tytuł :
Bisphenol S stimulates Leydig cell proliferation but inhibits differentiation in pubertal male rats through multiple mechanisms.
Autorzy :
Pan P; Department of Reproductive Medicine, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.
Wen Z; Department of Andrology, Chengdu Xi'nan Gynecological Hospital, Chengdu, China.
Ma F; Department of Obstetrics and Gynecology, The Second Affiliated Hospital and Yuying Children's Hospital, Wenzhou Medical University, Wenzhou, China.
Lei Z; Department of Andrology, Chengdu Xi'nan Gynecological Hospital, Chengdu, China.
Pan C; Department of Reproductive Medicine, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.
Fei Q; Department of Reproductive Medicine, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.
Tian E; Department of Andrology, Chengdu Xi'nan Gynecological Hospital, Chengdu, China.
Wang Y; Department of Obstetrics and Gynecology, The Second Affiliated Hospital and Yuying Children's Hospital, Wenzhou Medical University, Wenzhou, China.
Zhu Q; Department of Obstetrics and Gynecology, The Second Affiliated Hospital and Yuying Children's Hospital, Wenzhou Medical University, Wenzhou, China.
Li H; Department of Obstetrics and Gynecology, The Second Affiliated Hospital and Yuying Children's Hospital, Wenzhou Medical University, Wenzhou, China.
Li X; Department of Obstetrics and Gynecology, The Second Affiliated Hospital and Yuying Children's Hospital, Wenzhou Medical University, Wenzhou, China.
Zhong Y; Department of Andrology, Chengdu Xi'nan Gynecological Hospital, Chengdu, China.
Ge RS; Department of Obstetrics and Gynecology, The Second Affiliated Hospital and Yuying Children's Hospital, Wenzhou Medical University, Wenzhou, China.
Xu RA; Department of Pharmacy, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.
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Źródło :
Environmental toxicology [Environ Toxicol] 2023 Oct; Vol. 38 (10), pp. 2361-2376. Date of Electronic Publication: 2023 Jun 26.
Typ publikacji :
Journal Article
MeSH Terms :
Cholesterol Side-Chain Cleavage Enzyme*/metabolism
Testosterone*
Rats ; Male ; Animals ; Rats, Sprague-Dawley ; Leydig Cells/metabolism ; Cell Differentiation ; Cell Proliferation
Czasopismo naukowe
Tytuł :
Mitochondrial cytochrome P450 1B1 is involved in pregnenolone synthesis in human brain cells.
Autorzy :
Lin YC; Department of Pharmacology and Pharmaceutical Sciences, Alfred E. Mann School of Pharmacy and Pharmaceutical Sciences, University of Southern California, Los Angeles, California, USA.
Cheung G; Department of Pharmacology and Pharmaceutical Sciences, Alfred E. Mann School of Pharmacy and Pharmaceutical Sciences, University of Southern California, Los Angeles, California, USA.
Zhang Z; Department of Pharmacology and Pharmaceutical Sciences, Alfred E. Mann School of Pharmacy and Pharmaceutical Sciences, University of Southern California, Los Angeles, California, USA.
Papadopoulos V; Department of Pharmacology and Pharmaceutical Sciences, Alfred E. Mann School of Pharmacy and Pharmaceutical Sciences, University of Southern California, Los Angeles, California, USA. Electronic address: .
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Źródło :
The Journal of biological chemistry [J Biol Chem] 2023 Aug; Vol. 299 (8), pp. 105035. Date of Electronic Publication: 2023 Jul 11.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cholesterol Side-Chain Cleavage Enzyme*/genetics
Cytochrome P-450 CYP1B1*/metabolism
Pregnenolone*/biosynthesis
Humans ; Brain/metabolism ; Cytochrome P-450 CYP1A1/metabolism ; Hydroxycholesterols/metabolism ; Mitochondria/metabolism ; Neuroglia/metabolism ; RNA, Small Interfering/metabolism ; Steroids/metabolism
Czasopismo naukowe
Tytuł :
Comparative biochemical characterization of mammalian-derived CYP11A1s with cholesterol side-chain cleavage activities.
Autorzy :
Liu R; State Key Laboratory of Microbial Technology, Shandong University, Qingdao, Shandong 266237, China; Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, Qingdao, Shandong 266237, China.
Pan Y; State Key Laboratory of Microbial Technology, Shandong University, Qingdao, Shandong 266237, China.
Wang N; State Key Laboratory of Microbial Technology, Shandong University, Qingdao, Shandong 266237, China; College of Life Sciences, Shandong Normal University, Jinan, Shandong 250014, China.
Tang D; State Key Laboratory of Microbial Technology, Shandong University, Qingdao, Shandong 266237, China.
Urlacher VB; Institute of Biochemistry, Heinrich-Heine-University Düsseldorf, Universitätsstraße 1, Düsseldorf 40225, Germany.
Li S; State Key Laboratory of Microbial Technology, Shandong University, Qingdao, Shandong 266237, China; Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, Qingdao, Shandong 266237, China. Electronic address: .
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Źródło :
The Journal of steroid biochemistry and molecular biology [J Steroid Biochem Mol Biol] 2023 May; Vol. 229, pp. 106268. Date of Electronic Publication: 2023 Feb 09.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cholesterol Side-Chain Cleavage Enzyme*/genetics
Cholesterol Side-Chain Cleavage Enzyme*/metabolism
Isoenzymes*/metabolism
Cattle ; Animals ; Humans ; Cholesterol/metabolism ; Oxidation-Reduction ; Steroids ; Adrenodoxin/chemistry ; Mammals/metabolism
Czasopismo naukowe
Tytuł :
Spheroid formation and luteinization of granulosa cells of felids in a long-term 3D culture.
Autorzy :
Hryciuk MM; Leibniz Institute for Zoo and Wildlife Research, Department of Reproduction Biology, 10315, Berlin, Germany. Electronic address: .
Schröter F; Department of Cardiovascular Surgery, Heart Center Brandenburg, University Hospital Brandenburg Medical School, 16321, Bernau, Germany; Brandenburg Medical School, Faculty of Health Sciences Brandenburg, 14770, Brandenburg, Germany.
Hennicke L; Leibniz Institute for Zoo and Wildlife Research, Department of Reproduction Biology, 10315, Berlin, Germany.
Braun BC; Leibniz Institute for Zoo and Wildlife Research, Department of Reproduction Biology, 10315, Berlin, Germany.
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Źródło :
Differentiation; research in biological diversity [Differentiation] 2023 May-Jun; Vol. 131, pp. 38-48. Date of Electronic Publication: 2023 Apr 06.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cholesterol Side-Chain Cleavage Enzyme*/genetics
Cholesterol Side-Chain Cleavage Enzyme*/metabolism
Panthera*/metabolism
Female ; Cats ; Animals ; Granulosa Cells/metabolism ; Luteinization/physiology ; Multienzyme Complexes/metabolism ; Cells, Cultured
Czasopismo naukowe
Tytuł :
Pregnenolone and progesterone production from natural sterols using recombinant strain of Mycolicibacterium smegmatis mc  155 expressing mammalian steroidogenesis system.
Autorzy :
Karpov M; G.K. Skryabin Institute of Biochemistry and Physiology of Microorganisms, RAS, Federal Research Center 'Pushchino Scientific Center for Biological Research of the Russian Academy of Sciences', Pushchino, 142290, Russia. .
Strizhov N; G.K. Skryabin Institute of Biochemistry and Physiology of Microorganisms, RAS, Federal Research Center 'Pushchino Scientific Center for Biological Research of the Russian Academy of Sciences', Pushchino, 142290, Russia.
Novikova L; Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Leninskie Gory 1/40, Moscow, 119234, Russia.
Lobastova T; G.K. Skryabin Institute of Biochemistry and Physiology of Microorganisms, RAS, Federal Research Center 'Pushchino Scientific Center for Biological Research of the Russian Academy of Sciences', Pushchino, 142290, Russia.
Khomutov S; G.K. Skryabin Institute of Biochemistry and Physiology of Microorganisms, RAS, Federal Research Center 'Pushchino Scientific Center for Biological Research of the Russian Academy of Sciences', Pushchino, 142290, Russia.
Shutov A; G.K. Skryabin Institute of Biochemistry and Physiology of Microorganisms, RAS, Federal Research Center 'Pushchino Scientific Center for Biological Research of the Russian Academy of Sciences', Pushchino, 142290, Russia.
Kazantsev A; Chemistry Department, Lomonosov Moscow State University, Leninskie Gory 1/3, Moscow, 119991, Russia.
Donova M; G.K. Skryabin Institute of Biochemistry and Physiology of Microorganisms, RAS, Federal Research Center 'Pushchino Scientific Center for Biological Research of the Russian Academy of Sciences', Pushchino, 142290, Russia. .
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Źródło :
Microbial cell factories [Microb Cell Fact] 2024 Apr 09; Vol. 23 (1), pp. 105. Date of Electronic Publication: 2024 Apr 09.
Typ publikacji :
Journal Article
MeSH Terms :
Progesterone*
Phytosterols*
Cattle ; Animals ; Pregnenolone/metabolism ; Sterols ; Steroids ; Cholesterol/metabolism ; Cholesterol Side-Chain Cleavage Enzyme/genetics ; Cholesterol Side-Chain Cleavage Enzyme/metabolism ; Mammals/metabolism ; Ethers
Czasopismo naukowe
Tytuł :
Microbiota modulates the steroid response to acute immune stress in male mice.
Autorzy :
Vagnerová K; Institute of Physiology, Czech Academy of Sciences, Prague, Czechia.
Gazárková T; Department of Analytical Chemistry, Faculty of Pharmacy, Charles University, Hradec Králové, Czechia.
Vodička M; Institute of Physiology, Czech Academy of Sciences, Prague, Czechia.
Ergang P; Institute of Physiology, Czech Academy of Sciences, Prague, Czechia.
Klusoňová P; Institute of Physiology, Czech Academy of Sciences, Prague, Czechia.
Hudcovic T; Institute of Microbiology, Czech Academy of Sciences, Nový Hrádek, Czechia.
Šrůtková D; Institute of Microbiology, Czech Academy of Sciences, Nový Hrádek, Czechia.
Petr Hermanová P; Institute of Microbiology, Czech Academy of Sciences, Nový Hrádek, Czechia.
Nováková L; Department of Analytical Chemistry, Faculty of Pharmacy, Charles University, Hradec Králové, Czechia.
Pácha J; Institute of Physiology, Czech Academy of Sciences, Prague, Czechia.; Department of Physiology, Faculty of Science, Charles University, Prague, Czechia.
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Źródło :
Frontiers in immunology [Front Immunol] 2024 Feb 01; Vol. 15, pp. 1330094. Date of Electronic Publication: 2024 Feb 01 (Print Publication: 2024).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Hypothalamo-Hypophyseal System*/metabolism
Microbiota*
Male ; Mice ; Animals ; Cholesterol Side-Chain Cleavage Enzyme/genetics ; Cholesterol Side-Chain Cleavage Enzyme/metabolism ; Tandem Mass Spectrometry ; Pituitary-Adrenal System/metabolism ; Steroids/metabolism ; Corticosterone/metabolism
Czasopismo naukowe
Tytuł :
Effect of quercetin on granulosa cells development from hierarchical follicles in chicken.
Autorzy :
Li T; Jiangsu Key Laboratory of Sericultural Biology and Biotechnology, College of Biotechnology, Jiangsu University of Science and Technology, Zhenjiang, China.
Feng Y; Jiangsu Key Laboratory of Sericultural Biology and Biotechnology, College of Biotechnology, Jiangsu University of Science and Technology, Zhenjiang, China.
Chen Z; Jiangsu Key Laboratory of Sericultural Biology and Biotechnology, College of Biotechnology, Jiangsu University of Science and Technology, Zhenjiang, China.
Hou Q; Jiangsu Key Laboratory of Sericultural Biology and Biotechnology, College of Biotechnology, Jiangsu University of Science and Technology, Zhenjiang, China.
Serrano BR; Plant Protein and Bionatural Products Research Center, Havana, Cuba.
Barcenas AR; Plant Protein and Bionatural Products Research Center, Havana, Cuba.
Wu P; Jiangsu Key Laboratory of Sericultural Biology and Biotechnology, College of Biotechnology, Jiangsu University of Science and Technology, Zhenjiang, China.
Zhao W; Jiangsu Key Laboratory of Sericultural Biology and Biotechnology, College of Biotechnology, Jiangsu University of Science and Technology, Zhenjiang, China.
Shen M; Jiangsu Key Laboratory of Sericultural Biology and Biotechnology, College of Biotechnology, Jiangsu University of Science and Technology, Zhenjiang, China.; Laying Hen Breeding and Production Laboratory, Jiangsu Institute of Poultry Science, Yangzhou, China.
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Źródło :
British poultry science [Br Poult Sci] 2024 Feb; Vol. 65 (1), pp. 44-51. Date of Electronic Publication: 2023 Oct 23.
Typ publikacji :
Journal Article
MeSH Terms :
Progesterone*/metabolism
Progesterone*/pharmacology
Chickens*/genetics
Female ; Animals ; Quercetin/pharmacology ; Quercetin/metabolism ; Proliferating Cell Nuclear Antigen/genetics ; Proliferating Cell Nuclear Antigen/metabolism ; Proliferating Cell Nuclear Antigen/pharmacology ; Cholesterol Side-Chain Cleavage Enzyme/genetics ; Cholesterol Side-Chain Cleavage Enzyme/metabolism ; Granulosa Cells/physiology ; RNA, Messenger/genetics ; RNA, Messenger/metabolism
Czasopismo naukowe
Tytuł :
De novo steroidogenesis in tumor cells drives bone metastasis and osteoclastogenesis.
Autorzy :
Sandor LF; Department of Physiology, Semmelweis University School of Medicine, 1094 Budapest, Hungary.
Huh JB; Department of Physiology, Semmelweis University School of Medicine, 1094 Budapest, Hungary.
Benko P; Department of Physiology, Semmelweis University School of Medicine, 1094 Budapest, Hungary.
Hiraga T; Department of Histology and Cell Biology, Matsumoto Dental University, Shiojiri, Nagano 399-0781, Japan.
Poliska S; Department of Biochemistry and Molecular Biology, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.
Dobo-Nagy C; Department of Oral Diagnostics, Semmelweis University School of Dentistry, 1088 Budapest, Hungary.
Simpson JP; Mass Spectrometry Core, Edinburgh Clinical Research Facility, Queen's Medical Research Institute, University of Edinburgh, EH16 4TJ Edinburgh, UK.
Homer NZM; Mass Spectrometry Core, Edinburgh Clinical Research Facility, Queen's Medical Research Institute, University of Edinburgh, EH16 4TJ Edinburgh, UK; University of Edinburgh/BHF Centre for Cardiovascular Sciences, Queen's Medical Research Institute, University of Edinburgh, EH16 4TJ Edinburgh, UK.
Mahata B; Department of Pathology, University of Cambridge, Cambridge CB21QP Cambridgeshire, UK.
Gyori DS; Department of Physiology, Semmelweis University School of Medicine, 1094 Budapest, Hungary. Electronic address: .
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Źródło :
Cell reports [Cell Rep] 2024 Mar 26; Vol. 43 (3), pp. 113936. Date of Electronic Publication: 2024 Mar 13.
Typ publikacji :
Journal Article
MeSH Terms :
Bone Neoplasms*/metabolism
Breast Neoplasms*/pathology
Humans ; Female ; Osteogenesis ; Cholesterol Side-Chain Cleavage Enzyme/metabolism ; Cell Line, Tumor ; Osteoclasts/metabolism ; Pregnenolone/metabolism ; Cell Differentiation
Czasopismo naukowe
Tytuł :
Perfluorooctanoic acid inhibits androgen biosynthesis in rat immature Leydig cells.
Autorzy :
Zhang D; Department of Urology, The First Affiliated Hospital of Ningbo University, Ningbo, Zhejiang, China.
Hu J; Department of Urology, The First Affiliated Hospital of Ningbo University, Ningbo, Zhejiang, China.
Li H; Department of Urology, The First Affiliated Hospital of Ningbo University, Ningbo, Zhejiang, China.
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Źródło :
Environmental toxicology [Environ Toxicol] 2024 Mar; Vol. 39 (3), pp. 1700-1714. Date of Electronic Publication: 2023 Dec 05.
Typ publikacji :
Journal Article
MeSH Terms :
Leydig Cells*/metabolism
Fluorocarbons*/metabolism
Caprylates*
Male ; Rats ; Animals ; Androgens/metabolism ; Rats, Sprague-Dawley ; Cholesterol Side-Chain Cleavage Enzyme/metabolism ; RNA, Messenger/metabolism ; Testosterone
Czasopismo naukowe

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