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Wyświetlanie 1-20 z 237
Podgląd okładki
Tytuł :
The neuroprotective effects of AMN082 on neuronal apoptosis in rats after traumatic brain injury
Autorzy :
Chung-Che Lu
Tee-Tau Eric Nyam
Jinn-Rung Kuo
Yao-Lin Lee
Chung-Ching Chio
Che-Chuan Wang
Pokaż więcej
Temat :
AMN082
Traumatic brain injury
Nitrosative stress
Apoptosis
NMDA receptor
Neurosciences. Biological psychiatry. Neuropsychiatry
RC321-571
Neurophysiology and neuropsychology
QP351-495
Źródło :
BMC Neuroscience, Vol 22, Iss 1, Pp 1-14 (2021)
Opis pliku :
electronic resource
Relacje :
https://doaj.org/toc/1471-2202
Dostęp URL :
https://doaj.org/article/58ed97d6b8c045c8b095cfc94319a5e5
Czasopismo naukowe
Szczegóły Pełny tekst
Podgląd okładki
Tytuł :
Contribution of the mGluR7 receptor to antiparkinsonian-like effects in rats: a behavioral study with the selective agonist AMN082
Autorzy :
Konieczny, Jolanta
Lenda, Tomasz
Pokaż więcej
Źródło :
Pharmacological Reports. 65(5):1194-1203
Czasopismo naukowe
Szczegóły
Podgląd okładki
Tytuł :
The potential antidepressant action and adverse effects profile of scopolamine co-administered with the mGlu7 receptor allosteric agonist AMN082 in mice
Autorzy :
Podkowa, Karolina
Pilc, Andrzej
Podkowa, Adrian
Sałat, Kinga
Marciniak, Marcin
Pałucha-Poniewiera, Agnieszka
Pokaż więcej
Temat :
Male
Agonist
medicine.drug_class
Scopolamine
Morris water navigation task
Pharmacology
Receptors, Metabotropic Glutamate
Mice
03 medical and health sciences
Cellular and Molecular Neuroscience
chemistry.chemical_compound
0302 clinical medicine
Allosteric Regulation
AMN082
Excitatory Amino Acid Agonists
medicine
Animals
Benzhydryl Compounds
Maze Learning
Mice, Knockout
business.industry
Drug Synergism
Immobility Response, Tonic
Receptor antagonist
Antidepressive Agents
Tail suspension test
030227 psychiatry
Metabotropic receptor
chemistry
Metabotropic glutamate receptor
Rotarod Performance Test
business
Locomotion
030217 neurology & neurosurgery
Behavioural despair test
Źródło :
Neuropharmacology. 141:214-222
Dostęp URL :
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d7d451bd89d7e61162cbf04405bc092
https://doi.org/10.1016/j.neuropharm.2018.08.022
Szczegóły
Podgląd okładki
Tytuł :
Computationally Guided Identification of Allosteric Agonists of the Metabotropic Glutamate 7 Receptor
Autorzy :
José María Cid
Hilde Lavreysen
Laura Pérez-Benito
Fulgencio Tovar
Gary Tresadern
Andrés A. Trabanco
Alberto Fontana
Pokaż więcej
Temat :
Physiology
Cognitive Neuroscience
Allosteric regulation
CHO Cells
Neurotransmission
Receptors, Metabotropic Glutamate
Biochemistry
03 medical and health sciences
chemistry.chemical_compound
Cricetulus
0302 clinical medicine
Allosteric Regulation
AMN082
Cricetinae
Excitatory Amino Acid Agonists
Animals
Humans
Receptor
030304 developmental biology
0303 health sciences
Virtual screening
Glutamate receptor
Cell Biology
General Medicine
Rats
Molecular Docking Simulation
Metabotropic receptor
chemistry
Docking (molecular)
Microsomes, Liver
Neuroscience
030217 neurology & neurosurgery
Źródło :
ACS Chemical Neuroscience. 10:1043-1054
Dostęp URL :
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ceaacf11b71a291b8498fad52c8a6133
https://doi.org/10.1021/acschemneuro.8b00331
Szczegóły
Podgląd okładki
Tytuł :
Metabotropic glutamate receptor subtype 7 in the dorsal striatum oppositely modulates pain in sham and neuropathic rats
Autorzy :
Serena Boccella
Vito de Novellis
Nicola Serra
Ida Marabese
Livio Luongo
Sabatino Maione
Enza Palazzo
Antonio Farina
Francesca Guida
Monica Iannotta
Pokaż więcej
Temat :
Male
0301 basic medicine
medicine.medical_specialty
SNi
Microinjections
mGluR7
Glutamic Acid
Pain
Striatum
Receptors, Metabotropic Glutamate
Dorsal striatum
03 medical and health sciences
Cellular and Molecular Neuroscience
chemistry.chemical_compound
Mechanical allodynia
0302 clinical medicine
AMN082
Subthalamic Nucleus
Medullary dorsal reticular nucleus
Internal medicine
Basal ganglia
medicine
Animals
Benzhydryl Compounds
Neurons
Pharmacology
Benzoxazoles
Medulla Oblongata
Reticular Formation
Spared nerve injury
Glutamate receptor
Lidocaine
Sciatic Nerve
Corpus Striatum
Rats
Neuroprotective Agents
030104 developmental biology
Endocrinology
Nociception
chemistry
Hyperalgesia
Metabotropic glutamate receptor
Neuralgia
Rostral ventromedial medulla
030217 neurology & neurosurgery
Źródło :
Neuropharmacology. 135:86-99
Dostęp URL :
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e49e477c1d9b2a7e73a07d4793bb80d
https://doi.org/10.1016/j.neuropharm.2018.03.003
Szczegóły
Podgląd okładki
Tytuł :
Selective activation of metabotropic glutamate receptor 7 blocks paclitaxel-induced acute neuropathic pain and suppresses spinal glial reactivity in rats
Autorzy :
Changyu Jiang
Jiali Wang
Jiaman Wu
Shimin Yang
Zelin Huang
Xiyuan Ba
Guangyi Jin
Yue Hao
Pokaż więcej
Temat :
Male
Allosteric modulator
Paclitaxel
Glutamic Acid
Pharmacology
Receptors, Metabotropic Glutamate
Rats, Sprague-Dawley
03 medical and health sciences
Glutamatergic
chemistry.chemical_compound
0302 clinical medicine
AMN082
Allosteric Regulation
medicine
Excitatory Amino Acid Agonists
Animals
Benzhydryl Compounds
business.industry
Metabotropic glutamate receptor 7
Glutamate receptor
Acute Pain
030227 psychiatry
Rats
medicine.anatomical_structure
chemistry
Spinal Cord
Metabotropic glutamate receptor
Neuropathic pain
Neuralgia
business
030217 neurology & neurosurgery
Astrocyte
Źródło :
Psychopharmacology. 238(1)
Dostęp URL :
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0b3f456e79aa173ef8bd39c37d7d7e4
https://pubmed.ncbi.nlm.nih.gov/33089875
Szczegóły
Podgląd okładki
Tytuł :
Metabotropic glutamate receptor subtype 7 controls maternal care, maternal motivation and maternal aggression in mice
Autorzy :
Katharina Gryksa
Peter J. Flor
Angelika Bauer
Daniel Peterlik
Laura A. Mittmann
Nicole Uschold-Schmidt
Oliver J. Bosch
Pokaż więcej
Temat :
0301 basic medicine
Agonist
medicine.medical_specialty
medicine.drug_class
Receptor expression
Hippocampus
Prefrontal Cortex
Biology
Receptors, Metabotropic Glutamate
590 Tiere (Zoologie)
03 medical and health sciences
Behavioral Neuroscience
chemistry.chemical_compound
Glutamatergic
Mice
0302 clinical medicine
AMN082
Internal medicine
Genetics
medicine
Animals
Excitatory Amino Acid Agents
Benzhydryl Compounds
Maternal Behavior
Motivation
Glutamate receptor
MEDIAL PREFRONTAL CORTEX
NUCLEUS-ACCUMBENS
OLFACTORY BULBECTOMY
BEHAVIOR
RAT
STRESS
LOCALIZATION
AGONIST
BRAIN
ACTIVATION
knockout
metabotropic glutamate receptor
social behavior
spontaneous maternal behavior
strain difference
XAP044
Aggression
Mice, Inbred C57BL
030104 developmental biology
Endocrinology
Neurology
chemistry
Metabotropic glutamate receptor
Chromones
Knockout mouse
ddc:590
Female
030217 neurology & neurosurgery
Źródło :
Genes, brain, and behaviorREFERENCES. 19(1)
Opis pliku :
application/pdf
Dostęp URL :
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::395351d2fafe3bbebb67e0235f9942df
https://pubmed.ncbi.nlm.nih.gov/31793148
Szczegóły
Podgląd okładki
Tytuł :
The influence of AMN082, metabotropic glutamate receptor 7 (mGlu7) allosteric agonist on the acute and chronic antinociceptive effects of morphine in the tail-immersion test in mice: Comparison with mGlu5 and mGlu2/3 ligands
Autorzy :
Sylwia Talarek
K.K. Wojtanowski
Malgorzata Jenda-Wojtanowska
Kinga Gawel
Ewa Gibula-Bruzda
L. Komsta
Marta Marszalek-Grabska
Joanna Filarowska
Jolanta Kotlinska
Ewa Kędzierska
Pokaż więcej
Temat :
Male
Tail
0301 basic medicine
Agonist
Pyridines
Pyridones
medicine.drug_class
Experimental and Cognitive Psychology
Pharmacology
Receptors, Metabotropic Glutamate
Receptors, N-Methyl-D-Aspartate
Nociceptive Pain
Bridged Bicyclo Compounds
Mice
Random Allocation
03 medical and health sciences
Behavioral Neuroscience
chemistry.chemical_compound
0302 clinical medicine
Allosteric Regulation
AMN082
Excitatory Amino Acid Agonists
medicine
Animals
Benzhydryl Compounds
Analgesics
Dose-Response Relationship, Drug
Morphine
Metabotropic glutamate receptor 7
Glutamate receptor
Drug Tolerance
Thiazoles
030104 developmental biology
MTEP
chemistry
Metabotropic glutamate receptor
NMDA receptor
Dizocilpine Maleate
Excitatory Amino Acid Antagonists
030217 neurology & neurosurgery
medicine.drug
Źródło :
Physiology & Behavior. 185:112-120
Dostęp URL :
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::568b69d6f4a2be686c2a1846ff8c8bfe
https://doi.org/10.1016/j.physbeh.2017.12.035
Szczegóły
Podgląd okładki
Tytuł :
Pharmacological modulation of metabotropic glutamate receptor subtype 5 and 7 impairs extinction of social fear in a time-point-dependent manner
Autorzy :
Iulia Zoicas
David A. Slattery
Inga D. Neumann
Peter J. Flor
Pokaż więcej
Temat :
Male
0301 basic medicine
Agonist
Pyridines
medicine.drug_class
Receptor, Metabotropic Glutamate 5
Receptors, Metabotropic Glutamate
Extinction, Psychological
Mice
03 medical and health sciences
Behavioral Neuroscience
chemistry.chemical_compound
0302 clinical medicine
AMN082
Conditioning, Psychological
mental disorders
medicine
Animals
Excitatory Amino Acid Agents
Fear conditioning
Benzhydryl Compounds
Fear processing in the brain
Psychotropic Drugs
Metabotropic glutamate receptor 5
Fear
social sciences
Extinction (psychology)
humanities
Blockade
030104 developmental biology
Social Perception
chemistry
Metabotropic glutamate receptor
Mental Recall
Psychology
Neuroscience
030217 neurology & neurosurgery
Źródło :
Behavioural Brain Research. 328:57-61
Dostęp URL :
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::437bcbf6cdca7505b71d79dfee252886
https://doi.org/10.1016/j.bbr.2017.04.010
Szczegóły
Podgląd okładki
Tytuł :
Relief from detrimental consequences of chronic psychosocial stress in mice deficient for the metabotropic glutamate receptor subtype 7
Autorzy :
Daniel Peterlik
Robert Strasser
Peter J. Flor
Dominik Grabski
Christina Stangl
Dominic Schmidt
Anna Bludau
Nicole Uschold-Schmidt
Pokaż więcej
Temat :
Male
0301 basic medicine
Inflammation
Anxiety
Receptors, Metabotropic Glutamate
Bioinformatics
Mice
03 medical and health sciences
Cellular and Molecular Neuroscience
chemistry.chemical_compound
0302 clinical medicine
Adrenocorticotropic Hormone
AMN082
Downregulation and upregulation
medicine
Animals
Prefrontal cortex
Mice, Knockout
Pharmacology
Body Weight
Stressor
Blockade
Mice, Inbred C57BL
030104 developmental biology
chemistry
Metabotropic glutamate receptor
medicine.symptom
Corticosterone
Psychology
Neuroscience
Psychosocial
Stress, Psychological
030217 neurology & neurosurgery
Źródło :
Neuropharmacology. 115:139-148
Dostęp URL :
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e023e24da3c049fc286d67bf644ddef8
https://doi.org/10.1016/j.neuropharm.2016.04.036
Szczegóły
Podgląd okładki
Tytuł :
The neuroprotective effects of orthosteric agonists of group II and III mGluRs in primary neuronal cell cultures are dependent on developmental stage
Autorzy :
A. Greda
Danuta Jantas
Slawomir Golda
Michal Korostynski
W. Lason
Pokaż więcej
Temat :
0301 basic medicine
Agonist
Allosteric modulator
medicine.drug_class
Primary Cell Culture
Allosteric regulation
Glutamic Acid
Apoptosis
Cyclopentanes
Biology
Pharmacology
Receptors, Metabotropic Glutamate
Hippocampus
Neuroprotection
Bridged Bicyclo Compounds
Mice
03 medical and health sciences
Cellular and Molecular Neuroscience
chemistry.chemical_compound
0302 clinical medicine
AMN082
Cerebellum
medicine
Animals
Benzhydryl Compounds
Picolinic Acids
Cells, Cultured
Neurons
Aniline Compounds
Cell Death
Glutamate receptor
Tricarboxylic Acids
Staurosporine
HYDIA
Neuroprotective Agents
030104 developmental biology
nervous system
chemistry
Doxorubicin
Metabotropic glutamate receptor
Neuroscience
030217 neurology & neurosurgery
Źródło :
Neuropharmacology. 111:195-211
Dostęp URL :
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72b75ad858a8fd97aa078cd205895e41
https://doi.org/10.1016/j.neuropharm.2016.09.003
Szczegóły
Podgląd okładki
Tytuł :
Metabotropic Glutamate Receptors 7 within the Nucleus Accumbens are Involved in Relief Learning in Rats
Autorzy :
Evelyn Kahl
Markus Fendt
Pokaż więcej
Temat :
Male
0301 basic medicine
Agonist
Reflex, Startle
mGluR7
nucleus accumbens
medicine.drug_class
Motor Activity
Neuropsychological Tests
Nucleus accumbens
Receptors, Metabotropic Glutamate
Article
Nociceptive Pain
Rats, Sprague-Dawley
03 medical and health sciences
chemistry.chemical_compound
Catheters, Indwelling
0302 clinical medicine
AMN082
Memory
Excitatory Amino Acid Agonists
medicine
Animals
pain
rat
Pharmacology (medical)
Benzhydryl Compounds
Long-term depression
Pharmacology
Appetitive Behavior
Metabotropic glutamate receptor 7
Association Learning
General Medicine
Electric Stimulation
Psychiatry and Mental health
030104 developmental biology
Nociception
Neurology
chemistry
Metabotropic glutamate receptor
Neurology (clinical)
relief
Aversive Stimulus
Neuroscience
030217 neurology & neurosurgery
Źródło :
Scopus-Elsevier
Current Neuropharmacology
Dostęp URL :
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6975f338c2702f56c72783bb8f8d7388
https://doi.org/10.2174/1570159x13666150425002017
Szczegóły
Podgląd okładki
Tytuł :
Neuroprotective effects of the allosteric agonist of metabotropic glutamate receptor 7 AMN082 on oxygen-glucose deprivation- and kainate-induced neuronal cell death
Autorzy :
Helena Domin
Danuta Jantas
Maria Śmiałowska
Pokaż więcej
Temat :
Agonist
Kainic acid
medicine.drug_class
Excitotoxicity
Kainate receptor
Pharmacology
Receptors, Metabotropic Glutamate
medicine.disease_cause
Neuroprotection
Mice
Cellular and Molecular Neuroscience
chemistry.chemical_compound
Allosteric Regulation
AMN082
medicine
Animals
Benzhydryl Compounds
Cells, Cultured
Neurons
Kainic Acid
Cell Death
Dose-Response Relationship, Drug
Cell Biology
Receptor antagonist
Cell Hypoxia
Oxygen
Glucose
Neuroprotective Agents
nervous system
chemistry
Metabotropic glutamate receptor
Neuroscience
Źródło :
Neurochemistry International. 88:110-123
Dostęp URL :
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef414ec1cf10503e575510dd36c1211a
https://doi.org/10.1016/j.neuint.2014.12.010
Szczegóły
Wyświetlanie 1-20 z 237

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