Temat: "Pharmacology" - Prolib Integro

Starter badań:

Pharmacology.

The science of pharmacology includes the history, source, physical and chemical properties, and biochemical and physiological effects of drugs (therapeutic chemicals, diagnostic chemicals, toxins, and related substances).

Magill’s Medical Guide (Online Edition), 2023. 3p.

Skocz do pozycji: 1 1.

Tytuł :: Leveraging multi-omics data to empower quantitative systems pharmacology in immuno-oncology.
Autorzy :: Arulraj T; Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
Wang H; Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
Ippolito A; Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
Zhang S; Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
Fertig EJ; Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.; Department of Oncology, and the Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.; Department of Applied Mathematics and Statistics, Johns Hopkins University, Baltimore, MD, USA.
Popel AS; Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.; Department of Oncology, and the Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.; Pokaż więcej
Źródło :: Briefings in bioinformatics [Brief Bioinform] 2024 Mar 27; Vol. 25 (3).
Typ publikacji :: Journal Article
MeSH Terms :: Neoplasms*/drug therapy
Neoplasms*/genetics
Pharmacology*
Humans ; Multiomics ; Network Pharmacology ; Medical Oncology ; Computational Biology ; Tumor Microenvironment
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 2 2.

Tytuł :: Development of bispecific T cell engagers: harnessing quantitative systems pharmacology.
Autorzy :: Qi T; Division of Pharmacotherapy and Experimental Therapeutics, Eshelman School of Pharmacy, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
Liao X; Division of Pharmacotherapy and Experimental Therapeutics, Eshelman School of Pharmacy, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
Cao Y; Division of Pharmacotherapy and Experimental Therapeutics, Eshelman School of Pharmacy, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA; Lineberger Comprehensive Cancer Center, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA. Electronic address: .; Pokaż więcej
Źródło :: Trends in pharmacological sciences [Trends Pharmacol Sci] 2023 Dec; Vol. 44 (12), pp. 880-890. Date of Electronic Publication: 2023 Oct 17.
Typ publikacji :: Journal Article; Review
MeSH Terms :: Pharmacology*/methods
Antibodies, Bispecific*/pharmacology
Antibodies, Bispecific*/therapeutic use
Humans ; T-Lymphocytes ; Network Pharmacology ; Immunotherapy/methods
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 3 3.

Tytuł :: Role of pharmacometrics and systems pharmacology in facilitating efficient dose optimization in oncology.
Autorzy :: Jayachandran P; Regeneron Pharmaceuticals, Inc., Tarrytown, New York, USA.
Desikan R; Clinical Pharmacology Modeling & Simulation, GlaxoSmithKline (GSK), Stevenage, Hertfordshire, UK.
Krishnaswami S; Oncology Research and Development, Pfizer, Groton, Connecticut, USA.
Hennig S; Certara, Inc., Melbourne, Victoria, Australia.; School of Clinical Sciences, Faculty of Health, Queensland University of Technology, Brisbane, Queensland, Australia.; Pokaż więcej
Źródło :: CPT: pharmacometrics & systems pharmacology [CPT Pharmacometrics Syst Pharmacol] 2023 Nov; Vol. 12 (11), pp. 1569-1572. Date of Electronic Publication: 2023 Nov 03.
Typ publikacji :: Editorial
MeSH Terms :: Pharmacology, Clinical*
Pharmacology*
Humans ; Network Pharmacology ; Medical Oncology
: Opinia redakcyjna

Szczegóły Pełny tekst Pełny tekst

Skocz do pozycji: 4 4.

Tytuł :: Network pharmacology analysis and animal experiment validation of neuroinflammation inhibition by total ginsenoside in treating CSM.
Autorzy :: Li ZY; Spine Disease Institute, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China; Key Laboratory of Theory and Therapy of Muscles and Bones, Ministry of Education, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Dai YX; Spine Disease Institute, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China; Key Laboratory of Theory and Therapy of Muscles and Bones, Ministry of Education, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Wu ZM; Spine Disease Institute, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China; Key Laboratory of Theory and Therapy of Muscles and Bones, Ministry of Education, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Li G; Spine Disease Institute, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China; Key Laboratory of Theory and Therapy of Muscles and Bones, Ministry of Education, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Pu PM; Spine Disease Institute, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China; Key Laboratory of Theory and Therapy of Muscles and Bones, Ministry of Education, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Hu CW; Spine Disease Institute, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China; Key Laboratory of Theory and Therapy of Muscles and Bones, Ministry of Education, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Zhou LY; Department of Rehabilitation Medicine, The First Aliated Hospital of Nanjing Medical University, Nanjing, China.
Zhu K; Spine Disease Institute, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China; Key Laboratory of Theory and Therapy of Muscles and Bones, Ministry of Education, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Shu B; Spine Disease Institute, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China; Key Laboratory of Theory and Therapy of Muscles and Bones, Ministry of Education, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Wang YJ; Spine Disease Institute, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China; Key Laboratory of Theory and Therapy of Muscles and Bones, Ministry of Education, Shanghai University of Traditional Chinese Medicine, Shanghai, China. Electronic address: .
Cui XJ; Spine Disease Institute, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China; Key Laboratory of Theory and Therapy of Muscles and Bones, Ministry of Education, Shanghai University of Traditional Chinese Medicine, Shanghai, China. Electronic address: .
Yao M; Spine Disease Institute, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, China; Key Laboratory of Theory and Therapy of Muscles and Bones, Ministry of Education, Shanghai University of Traditional Chinese Medicine, Shanghai, China. Electronic address: .; Pokaż więcej
Źródło :: Phytomedicine : international journal of phytotherapy and phytopharmacology [Phytomedicine] 2024 Apr; Vol. 126, pp. 155073. Date of Electronic Publication: 2023 Sep 20.
Typ publikacji :: Journal Article
MeSH Terms :: Spinal Cord Compression*
Ginsenosides*/pharmacology
Animal Experimentation*
Spinal Cord Diseases*
Drugs, Chinese Herbal*/pharmacology
Humans ; Animals ; Rats ; Interleukin-17 ; NLR Family, Pyrin Domain-Containing 3 Protein ; NF-kappa B ; Chromatography, Liquid ; Molecular Docking Simulation ; Myeloid Differentiation Factor 88 ; Network Pharmacology ; Neuroinflammatory Diseases ; Phosphatidylinositol 3-Kinases ; Toll-Like Receptor 4 ; Tandem Mass Spectrometry
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 5 5.

Tytuł :: Integrating transcriptomics and network pharmacology to reveal the mechanisms of total Rhizoma Coptidis alkaloids against nonalcoholic steatohepatitis.
Autorzy :: Li J; Engineering Research Center of Coptis Development and Utilization (Ministry of Education), College of Pharmaceutical Sciences, Southwest University, Chongqing, 400715, China. Electronic address: .
Ma Z; School of Life Sciences, Southwest University, Chongqing, 400715, China. Electronic address: .
Yang Z; Engineering Research Center of Coptis Development and Utilization (Ministry of Education), College of Pharmaceutical Sciences, Southwest University, Chongqing, 400715, China. Electronic address: .
Yang M; Engineering Research Center of Coptis Development and Utilization (Ministry of Education), College of Pharmaceutical Sciences, Southwest University, Chongqing, 400715, China. Electronic address: .
Li C; Engineering Research Center of Coptis Development and Utilization (Ministry of Education), College of Pharmaceutical Sciences, Southwest University, Chongqing, 400715, China. Electronic address: .
Li M; School of Life Sciences, Southwest University, Chongqing, 400715, China. Electronic address: .
Li X; School of Life Sciences, Southwest University, Chongqing, 400715, China. Electronic address: .
Chen X; School of Life Sciences, Southwest University, Chongqing, 400715, China. Electronic address: .
Ma H; Engineering Research Center of Coptis Development and Utilization (Ministry of Education), College of Pharmaceutical Sciences, Southwest University, Chongqing, 400715, China. Electronic address: .
Chen W; Department of Gastroenterology, Chongqing Hospital of Traditional Chinese Medicine, Chongqing, 400000, China. Electronic address: .
Ye X; School of Life Sciences, Southwest University, Chongqing, 400715, China. Electronic address: .
Li X; Engineering Research Center of Coptis Development and Utilization (Ministry of Education), College of Pharmaceutical Sciences, Southwest University, Chongqing, 400715, China. Electronic address: .; Pokaż więcej
Źródło :: Journal of ethnopharmacology [J Ethnopharmacol] 2024 Mar 25; Vol. 322, pp. 117600. Date of Electronic Publication: 2023 Dec 14.
Typ publikacji :: Journal Article
MeSH Terms :: Non-alcoholic Fatty Liver Disease*/metabolism
Carcinoma, Hepatocellular*/drug therapy
Alkaloids*/pharmacology
Alkaloids*/therapeutic use
Drugs, Chinese Herbal*/pharmacology
Drugs, Chinese Herbal*/therapeutic use
Antineoplastic Agents*
Liver Neoplasms*/drug therapy
Humans ; Mice ; Animals ; Matrix Metalloproteinase 9 ; Proto-Oncogene Proteins c-akt ; Phosphatidylinositol 3-Kinases ; Network Pharmacology ; PPAR gamma ; Gene Expression Profiling ; ErbB Receptors
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 6 6.

Tytuł :: Exploring the hypoglycemic mechanism of chlorogenic acids from Pyrrosia petiolosa (Christ) Ching on type 2 diabetes mellitus based on network pharmacology and transcriptomics strategy.
Autorzy :: He H; College of Pharmacy, Guizhou University of Traditional Chinese Medicine, No. 4 Dongqingnan Road, Huaxi District, Guiyang, Guizhou 550025, PR China.
Wei Q; College of Pharmacy, Guizhou University of Traditional Chinese Medicine, No. 4 Dongqingnan Road, Huaxi District, Guiyang, Guizhou 550025, PR China.
Chang J; College of Pharmacy, Guizhou University of Traditional Chinese Medicine, No. 4 Dongqingnan Road, Huaxi District, Guiyang, Guizhou 550025, PR China.
Yi X; Second Affiliated Hospital, Guizhou University of Traditional Chinese Medicine, No. 32 Feishan Road, Nanming District, Guiyang, Guizhou 550002, PR China.
Yu X; College of Pharmacy, Guizhou University of Traditional Chinese Medicine, No. 4 Dongqingnan Road, Huaxi District, Guiyang, Guizhou 550025, PR China.
Luo G; College of Pharmacy, Guizhou University of Traditional Chinese Medicine, No. 4 Dongqingnan Road, Huaxi District, Guiyang, Guizhou 550025, PR China.
Li X; College of Pharmacy, Guizhou University of Traditional Chinese Medicine, No. 4 Dongqingnan Road, Huaxi District, Guiyang, Guizhou 550025, PR China. Electronic address: .
Yang W; College of Pharmacy, Guizhou University of Traditional Chinese Medicine, No. 4 Dongqingnan Road, Huaxi District, Guiyang, Guizhou 550025, PR China. Electronic address: .
Long Y; College of Pharmacy, Guizhou University of Traditional Chinese Medicine, No. 4 Dongqingnan Road, Huaxi District, Guiyang, Guizhou 550025, PR China. Electronic address: .; Pokaż więcej
Źródło :: Journal of ethnopharmacology [J Ethnopharmacol] 2024 Mar 25; Vol. 322, pp. 117580. Date of Electronic Publication: 2023 Dec 16.
Typ publikacji :: Journal Article
MeSH Terms :: Diabetes Mellitus, Type 2*/drug therapy
Diabetes Mellitus, Type 2*/genetics
Drugs, Chinese Herbal*/pharmacology
Drugs, Chinese Herbal*/therapeutic use
Animals ; Rats ; Chlorogenic Acid/pharmacology ; Chlorogenic Acid/therapeutic use ; Gene Expression Profiling ; Hypoglycemic Agents/pharmacology ; Hypoglycemic Agents/therapeutic use ; Molecular Docking Simulation ; Network Pharmacology ; RNA, Messenger
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 7 7.

Tytuł :: [ Jianpi Zishen granule inhibits podocyte autophagy in systemic lupus erythematosus: a network pharmacology and clinical study].
Autorzy :: Chen J; First Clinical College, Anhui University of Chinese Medicine, Hefei 230000, China.
Huang C; Department of Rheumatology and Immunology, First Affiliated Hospital of Anhui University of Chinese Medicine, Hefei 230031, China.
Li M; Department of Rheumatology and Immunology, First Affiliated Hospital of Anhui University of Chinese Medicine, Hefei 230031, China.; Pokaż więcej
Źródło :: Nan fang yi ke da xue xue bao = Journal of Southern Medical University [Nan Fang Yi Ke Da Xue Xue Bao] 2024 Mar 20; Vol. 44 (3), pp. 465-473.
Typ publikacji :: Randomized Controlled Trial; English Abstract; Journal Article
MeSH Terms :: Podocytes*/metabolism
Lupus Erythematosus, Systemic*/drug therapy
Lupus Erythematosus, Systemic*/metabolism
Drugs, Chinese Herbal*/pharmacology
Drugs, Chinese Herbal*/therapeutic use
Humans ; Janus Kinases/metabolism ; Janus Kinases/pharmacology ; Janus Kinases/therapeutic use ; Signal Transduction ; Molecular Docking Simulation ; Network Pharmacology ; Phosphatidylinositol 3-Kinases/metabolism ; STAT Transcription Factors/metabolism ; STAT Transcription Factors/pharmacology ; STAT Transcription Factors/therapeutic use ; Autophagy
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 8 8.

Tytuł :: Molecular mechanism of Xiaohuoluo wan for rheumatoid arthritis by integrating in vitro and in vivo chemomics and network pharmacology.
Autorzy :: Qin W; School of Life Sciences, Beijing University of Chinese Medicine, Beijing, China.
Zhang K; School of Life Sciences, Beijing University of Chinese Medicine, Beijing, China.
Yu Z; School of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing, China.
Liu H; School of Life Sciences, Beijing University of Chinese Medicine, Beijing, China.
Li H; School of Life Sciences, Beijing University of Chinese Medicine, Beijing, China.
Dong L; School of Life Sciences, Beijing University of Chinese Medicine, Beijing, China.
Han D; School of Life Sciences, Beijing University of Chinese Medicine, Beijing, China.
Li T; School of Life Sciences, Beijing University of Chinese Medicine, Beijing, China.; Pokaż więcej
Źródło :: Biomedical chromatography : BMC [Biomed Chromatogr] 2024 Mar; Vol. 38 (3), pp. e5801. Date of Electronic Publication: 2023 Dec 18.
Typ publikacji :: Journal Article
MeSH Terms :: Arthritis, Rheumatoid*/drug therapy
Drugs, Chinese Herbal*/pharmacology
Humans ; Network Pharmacology ; Chromatography, Liquid ; Tandem Mass Spectrometry ; Anti-Inflammatory Agents/pharmacology
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 9 9.

Tytuł :: Polyphenol-enriched Penthorum chinense Pursh ameliorates alcohol-related liver injury through Ras/Raf/MEK/ERK pathway: Integrating network pharmacology and experiment validation.
Autorzy :: Li R; School of Pharmacy, Chengdu University, Chengdu, 610106, Sichuan, PR China; School of Food and Biological Engineering, Key Laboratory of Coarse Cereal Processing, Ministry of Agriculture and Rural Affairs, Sichuan Engineering & Technology Research Center of Coarse Cereal Industralization, Chengdu University, Chengdu, 610106, Sichuan, PR China. Electronic address: .
Wu D; School of Food and Biological Engineering, Key Laboratory of Coarse Cereal Processing, Ministry of Agriculture and Rural Affairs, Sichuan Engineering & Technology Research Center of Coarse Cereal Industralization, Chengdu University, Chengdu, 610106, Sichuan, PR China. Electronic address: DTWu_.
Hu J; School of Pharmacy, Chengdu University, Chengdu, 610106, Sichuan, PR China; School of Food and Biological Engineering, Key Laboratory of Coarse Cereal Processing, Ministry of Agriculture and Rural Affairs, Sichuan Engineering & Technology Research Center of Coarse Cereal Industralization, Chengdu University, Chengdu, 610106, Sichuan, PR China. Electronic address: .
Ma Y; School of Food and Biological Engineering, Key Laboratory of Coarse Cereal Processing, Ministry of Agriculture and Rural Affairs, Sichuan Engineering & Technology Research Center of Coarse Cereal Industralization, Chengdu University, Chengdu, 610106, Sichuan, PR China. Electronic address: .
Ba Y; School of Food and Biological Engineering, Key Laboratory of Coarse Cereal Processing, Ministry of Agriculture and Rural Affairs, Sichuan Engineering & Technology Research Center of Coarse Cereal Industralization, Chengdu University, Chengdu, 610106, Sichuan, PR China. Electronic address: .
Zou L; School of Food and Biological Engineering, Key Laboratory of Coarse Cereal Processing, Ministry of Agriculture and Rural Affairs, Sichuan Engineering & Technology Research Center of Coarse Cereal Industralization, Chengdu University, Chengdu, 610106, Sichuan, PR China. Electronic address: .
Hu Y; School of Pharmacy, Chengdu University, Chengdu, 610106, Sichuan, PR China; School of Food and Biological Engineering, Key Laboratory of Coarse Cereal Processing, Ministry of Agriculture and Rural Affairs, Sichuan Engineering & Technology Research Center of Coarse Cereal Industralization, Chengdu University, Chengdu, 610106, Sichuan, PR China. Electronic address: .; Pokaż więcej
Źródło :: Journal of ethnopharmacology [J Ethnopharmacol] 2024 Mar 01; Vol. 321, pp. 117513. Date of Electronic Publication: 2023 Nov 29.
Typ publikacji :: Journal Article
MeSH Terms :: Saxifragales*/chemistry
Drugs, Chinese Herbal*/pharmacology
Mice ; Animals ; Polyphenols/pharmacology ; Polyphenols/therapeutic use ; Polyphenols/metabolism ; MAP Kinase Signaling System ; Quercetin/pharmacology ; Chromatography, Liquid ; Apigenin/pharmacology ; Molecular Docking Simulation ; Network Pharmacology ; Tandem Mass Spectrometry ; Ethanol/pharmacology ; Liver ; Mitogen-Activated Protein Kinase Kinases/metabolism
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 10 10.

Tytuł :: Essential oil from Fructus Alpiniae zerumbet ameliorates vascular endothelial cell senescence in diabetes by regulating PPAR-γ signalling: A 4D label-free quantitative proteomics and network pharmacology study.
Autorzy :: Liao J; The State Key Laboratory of Functions and Applications of Medicinal Plants, Guizhou Medical University, 550025, Guiyang, China; The Department of Pharmacology of Materia Medica (The High Efficacy Application of Natural Medicinal Resources Engineering Center of Guizhou Province and the High Educational Key Laboratory of Guizhou Province for Natural Medicinal Pharmacology and Druggability), School of Pharmaceutical Sciences, Guizhou Medical University, 550025, Guiyang, China; The Key Laboratory of Optimal Utilization of Natural Medicine Resources (The Union Key Laboratory of Guiyang City-Guizhou Medical University), School of Pharmaceutical Sciences, Guizhou Medical University, 550025, Guiyang, China. Electronic address: .
Fu L; The State Key Laboratory of Functions and Applications of Medicinal Plants, Guizhou Medical University, 550025, Guiyang, China; The Department of Pharmacology of Materia Medica (The High Efficacy Application of Natural Medicinal Resources Engineering Center of Guizhou Province and the High Educational Key Laboratory of Guizhou Province for Natural Medicinal Pharmacology and Druggability), School of Pharmaceutical Sciences, Guizhou Medical University, 550025, Guiyang, China; The Key Laboratory of Optimal Utilization of Natural Medicine Resources (The Union Key Laboratory of Guiyang City-Guizhou Medical University), School of Pharmaceutical Sciences, Guizhou Medical University, 550025, Guiyang, China. Electronic address: .
Tai S; The State Key Laboratory of Functions and Applications of Medicinal Plants, Guizhou Medical University, 550025, Guiyang, China; The Department of Pharmacology of Materia Medica (The High Efficacy Application of Natural Medicinal Resources Engineering Center of Guizhou Province and the High Educational Key Laboratory of Guizhou Province for Natural Medicinal Pharmacology and Druggability), School of Pharmaceutical Sciences, Guizhou Medical University, 550025, Guiyang, China; The Key Laboratory of Optimal Utilization of Natural Medicine Resources (The Union Key Laboratory of Guiyang City-Guizhou Medical University), School of Pharmaceutical Sciences, Guizhou Medical University, 550025, Guiyang, China. Electronic address: .
Xu Y; The State Key Laboratory of Functions and Applications of Medicinal Plants, Guizhou Medical University, 550025, Guiyang, China; The Department of Pharmacology of Materia Medica (The High Efficacy Application of Natural Medicinal Resources Engineering Center of Guizhou Province and the High Educational Key Laboratory of Guizhou Province for Natural Medicinal Pharmacology and Druggability), School of Pharmaceutical Sciences, Guizhou Medical University, 550025, Guiyang, China; The Key Laboratory of Optimal Utilization of Natural Medicine Resources (The Union Key Laboratory of Guiyang City-Guizhou Medical University), School of Pharmaceutical Sciences, Guizhou Medical University, 550025, Guiyang, China. Electronic address: .
Wang S; The State Key Laboratory of Functions and Applications of Medicinal Plants, Guizhou Medical University, 550025, Guiyang, China; The Department of Pharmacology of Materia Medica (The High Efficacy Application of Natural Medicinal Resources Engineering Center of Guizhou Province and the High Educational Key Laboratory of Guizhou Province for Natural Medicinal Pharmacology and Druggability), School of Pharmaceutical Sciences, Guizhou Medical University, 550025, Guiyang, China; The Key Laboratory of Optimal Utilization of Natural Medicine Resources (The Union Key Laboratory of Guiyang City-Guizhou Medical University), School of Pharmaceutical Sciences, Guizhou Medical University, 550025, Guiyang, China. Electronic address: .
Guo L; The Key Laboratory of Optimal Utilization of Natural Medicine Resources (The Union Key Laboratory of Guiyang City-Guizhou Medical University), School of Pharmaceutical Sciences, Guizhou Medical University, 550025, Guiyang, China. Electronic address: .
Guo D; The State Key Laboratory of Functions and Applications of Medicinal Plants, Guizhou Medical University, 550025, Guiyang, China; The Department of Pharmacology of Materia Medica (The High Efficacy Application of Natural Medicinal Resources Engineering Center of Guizhou Province and the High Educational Key Laboratory of Guizhou Province for Natural Medicinal Pharmacology and Druggability), School of Pharmaceutical Sciences, Guizhou Medical University, 550025, Guiyang, China; The Key Laboratory of Optimal Utilization of Natural Medicine Resources (The Union Key Laboratory of Guiyang City-Guizhou Medical University), School of Pharmaceutical Sciences, Guizhou Medical University, 550025, Guiyang, China. Electronic address: .
Du Y; The State Key Laboratory of Functions and Applications of Medicinal Plants, Guizhou Medical University, 550025, Guiyang, China; The Department of Pharmacology of Materia Medica (The High Efficacy Application of Natural Medicinal Resources Engineering Center of Guizhou Province and the High Educational Key Laboratory of Guizhou Province for Natural Medicinal Pharmacology and Druggability), School of Pharmaceutical Sciences, Guizhou Medical University, 550025, Guiyang, China; The Key Laboratory of Optimal Utilization of Natural Medicine Resources (The Union Key Laboratory of Guiyang City-Guizhou Medical University), School of Pharmaceutical Sciences, Guizhou Medical University, 550025, Guiyang, China. Electronic address: .
He J; The State Key Laboratory of Functions and Applications of Medicinal Plants, Guizhou Medical University, 550025, Guiyang, China; The Department of Pharmacology of Materia Medica (The High Efficacy Application of Natural Medicinal Resources Engineering Center of Guizhou Province and the High Educational Key Laboratory of Guizhou Province for Natural Medicinal Pharmacology and Druggability), School of Pharmaceutical Sciences, Guizhou Medical University, 550025, Guiyang, China; The Key Laboratory of Optimal Utilization of Natural Medicine Resources (The Union Key Laboratory of Guiyang City-Guizhou Medical University), School of Pharmaceutical Sciences, Guizhou Medical University, 550025, Guiyang, China. Electronic address: .
Yang H; Department of Pharmacy, Guiyang Maternal and Child Health Care Hospital, Guiyang, 550003, Guizhou, China. Electronic address: .
Hu X; The State Key Laboratory of Functions and Applications of Medicinal Plants, Guizhou Medical University, 550025, Guiyang, China; The Department of Pharmacology of Materia Medica (The High Efficacy Application of Natural Medicinal Resources Engineering Center of Guizhou Province and the High Educational Key Laboratory of Guizhou Province for Natural Medicinal Pharmacology and Druggability), School of Pharmaceutical Sciences, Guizhou Medical University, 550025, Guiyang, China; The Key Laboratory of Optimal Utilization of Natural Medicine Resources (The Union Key Laboratory of Guiyang City-Guizhou Medical University), School of Pharmaceutical Sciences, Guizhou Medical University, 550025, Guiyang, China; The Key Laboratory of Endemic and Ethnic Diseases of Ministry of Education, Guizhou Medical University, 550004, Guiyang, China. Electronic address: .
Tao L; The State Key Laboratory of Functions and Applications of Medicinal Plants, Guizhou Medical University, 550025, Guiyang, China; The Department of Pharmacology of Materia Medica (The High Efficacy Application of Natural Medicinal Resources Engineering Center of Guizhou Province and the High Educational Key Laboratory of Guizhou Province for Natural Medicinal Pharmacology and Druggability), School of Pharmaceutical Sciences, Guizhou Medical University, 550025, Guiyang, China; The Key Laboratory of Optimal Utilization of Natural Medicine Resources (The Union Key Laboratory of Guiyang City-Guizhou Medical University), School of Pharmaceutical Sciences, Guizhou Medical University, 550025, Guiyang, China; The Key Laboratory of Endemic and Ethnic Diseases of Ministry of Education, Guizhou Medical University, 550004, Guiyang, China. Electronic address: .
Shen X; The State Key Laboratory of Functions and Applications of Medicinal Plants, Guizhou Medical University, 550025, Guiyang, China; The Department of Pharmacology of Materia Medica (The High Efficacy Application of Natural Medicinal Resources Engineering Center of Guizhou Province and the High Educational Key Laboratory of Guizhou Province for Natural Medicinal Pharmacology and Druggability), School of Pharmaceutical Sciences, Guizhou Medical University, 550025, Guiyang, China; The Key Laboratory of Optimal Utilization of Natural Medicine Resources (The Union Key Laboratory of Guiyang City-Guizhou Medical University), School of Pharmaceutical Sciences, Guizhou Medical University, 550025, Guiyang, China; The Key Laboratory of Endemic and Ethnic Diseases of Ministry of Education, Guizhou Medical University, 550004, Guiyang, China. Electronic address: .; Pokaż więcej
Źródło :: Journal of ethnopharmacology [J Ethnopharmacol] 2024 Mar 01; Vol. 321, pp. 117550. Date of Electronic Publication: 2023 Dec 06.
Typ publikacji :: Journal Article
MeSH Terms :: Diabetes Mellitus, Experimental*/drug therapy
Diabetes Mellitus, Experimental*/metabolism
Oils, Volatile*/pharmacology
Humans ; Mice ; Animals ; Endothelial Cells ; PPAR gamma/metabolism ; Rosiglitazone/metabolism ; Rosiglitazone/pharmacology ; Reactive Oxygen Species/metabolism ; Molecular Docking Simulation ; Network Pharmacology ; Proteomics ; RNA, Small Interfering ; Glucose/metabolism
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 11 11.

Tytuł :: Prevention of neointimal hyperplasia after coronary artery bypass graft via local delivery of sirolimus and rosuvastatin: network pharmacology and in vivo validation.
Autorzy :: Ryu JY; Division of Cardiovascular Surgery, Department of Thoracic and Cardiovascular Surgery, Severance Cardiovascular Hospital, Yonsei University College of Medicine, Seoul, 03722, South Korea.
Jang EH; Division of Cardiovascular Surgery, Department of Thoracic and Cardiovascular Surgery, Severance Cardiovascular Hospital, Yonsei University College of Medicine, Seoul, 03722, South Korea.
Lee J; School of Mechanical Engineering, Yonsei University, Seoul, 03722, South Korea.; Department of Mechanical Engineering, University of Minnesota, Minneapolis, MN, 55455, USA.
Kim JH; Division of Cardiovascular Surgery, Department of Thoracic and Cardiovascular Surgery, Severance Cardiovascular Hospital, Yonsei University College of Medicine, Seoul, 03722, South Korea.
Youn YN; Division of Cardiovascular Surgery, Department of Thoracic and Cardiovascular Surgery, Severance Cardiovascular Hospital, Yonsei University College of Medicine, Seoul, 03722, South Korea. .; Pokaż więcej
Źródło :: Journal of translational medicine [J Transl Med] 2024 Feb 16; Vol. 22 (1), pp. 166. Date of Electronic Publication: 2024 Feb 16.
Typ publikacji :: Journal Article
MeSH Terms :: Sirolimus*/pharmacology
Sirolimus*/therapeutic use
Drugs, Chinese Herbal*
Animals ; Rabbits ; Rosuvastatin Calcium/pharmacology ; Rosuvastatin Calcium/therapeutic use ; Hyperplasia/drug therapy ; Matrix Metalloproteinase 9 ; Network Pharmacology ; Proto-Oncogene Proteins c-akt ; Neointima ; Coronary Artery Bypass/adverse effects
: Czasopismo naukowe

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Skocz do pozycji: 12 12.

Tytuł :: Network Pharmacology and Experimental Verifications to Discover Scutellaria baicalensis Georgi's Effects on Joint Inflammation, Destruction, and Pain in Osteoarthritis.
Autorzy :: Jo HG; Department of Herbal Pharmacology, College of Korean Medicine, Gachon University, 1342 Seongnamdae-ro, Sujeong-gu, Seongnam-si 13120, Republic of Korea.; Naturalis Inc., 6 Daewangpangyo-ro, Bundang-gu, Seongnam-si 13549, Republic of Korea.
Baek CY; Department of Herbal Pharmacology, College of Korean Medicine, Gachon University, 1342 Seongnamdae-ro, Sujeong-gu, Seongnam-si 13120, Republic of Korea.
Song HS; Department of Acupuncture & Moxibustion Medicine, College of Korean Medicine, Gachon University, 1342 Seongnamdae-ro, Sujeong-gu, Seongnam-si 13120, Republic of Korea.
Lee D; Department of Herbal Pharmacology, College of Korean Medicine, Gachon University, 1342 Seongnamdae-ro, Sujeong-gu, Seongnam-si 13120, Republic of Korea.; Pokaż więcej
Źródło :: International journal of molecular sciences [Int J Mol Sci] 2024 Feb 09; Vol. 25 (4). Date of Electronic Publication: 2024 Feb 09.
Typ publikacji :: Journal Article
MeSH Terms :: Osteoarthritis*/drug therapy
Drugs, Chinese Herbal*/pharmacology
Network Pharmacology ; Scutellaria baicalensis ; Anti-Inflammatory Agents/pharmacology ; Anti-Inflammatory Agents/therapeutic use ; Inflammation/drug therapy ; Pain/drug therapy ; Molecular Docking Simulation
: Czasopismo naukowe

Szczegóły Pełny tekst Pełny tekst

Skocz do pozycji: 13 13.

Tytuł :: Uncovering the Mechanism of Chinese Hawthorn Leaf on Myocardial Ischemia Based on Network Pharmacology, Molecular Docking Verification, and In Vitro Studies.
Autorzy :: Gao J; Hebei Key Laboratory of Study and Exploitation of Chinese Medicine, Chengde Medical College, Anyuan Road, Shuangqiao District, Chengde, 067000, Hebei, China.
Wang Y; Hebei Key Laboratory of Study and Exploitation of Chinese Medicine, Chengde Medical College, Anyuan Road, Shuangqiao District, Chengde, 067000, Hebei, China.
Xiong H; Hebei Key Laboratory of Study and Exploitation of Chinese Medicine, Chengde Medical College, Anyuan Road, Shuangqiao District, Chengde, 067000, Hebei, China.
Zhao S; Hebei Key Laboratory of Study and Exploitation of Chinese Medicine, Chengde Medical College, Anyuan Road, Shuangqiao District, Chengde, 067000, Hebei, China.
He M; Hebei Key Laboratory of Study and Exploitation of Chinese Medicine, Chengde Medical College, Anyuan Road, Shuangqiao District, Chengde, 067000, Hebei, China.
He M; Hebei Key Laboratory of Study and Exploitation of Chinese Medicine, Chengde Medical College, Anyuan Road, Shuangqiao District, Chengde, 067000, Hebei, China.
Pan H; Hebei Key Laboratory of Study and Exploitation of Chinese Medicine, Chengde Medical College, Anyuan Road, Shuangqiao District, Chengde, 067000, Hebei, China. .; Pokaż więcej
Źródło :: Cardiovascular toxicology [Cardiovasc Toxicol] 2024 Feb; Vol. 24 (2), pp. 171-183. Date of Electronic Publication: 2024 Feb 20.
Typ publikacji :: Journal Article
MeSH Terms :: Crataegus*
Coronary Artery Disease*
Myocardial Ischemia*/drug therapy
Myocardial Ischemia*/genetics
Drugs, Chinese Herbal*/pharmacology
Humans ; Molecular Docking Simulation ; Network Pharmacology ; Phosphatidylinositol 3-Kinases ; Proto-Oncogene Proteins c-akt ; Quercetin/pharmacology ; Databases, Genetic
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Szczegóły

Skocz do pozycji: 14 14.

Tytuł :: Exploration of the immuno-adjuvant effect and mechanism of Anemoside B4 through network pharmacology and experiment verification.
Autorzy :: Shen L; College of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China. Electronic address: .
Luo H; College of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China.
Fan L; College of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China.
Su Z; College of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 610075, China.
Yu S; College of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China.
Cao S; College of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China.
Wu X; College of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China.; Pokaż więcej
Źródło :: Phytomedicine : international journal of phytotherapy and phytopharmacology [Phytomedicine] 2024 Feb; Vol. 124, pp. 155302. Date of Electronic Publication: 2023 Dec 19.
Typ publikacji :: Journal Article
MeSH Terms :: NF-kappa B*/metabolism
Saponins*/pharmacology
Saponins*/metabolism
Animals ; Mice ; Humans ; Toll-Like Receptor 4/metabolism ; Network Pharmacology ; Adjuvants, Immunologic/pharmacology ; Cytokines/metabolism ; Adjuvants, Pharmaceutic ; Dendritic Cells
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Szczegóły

Skocz do pozycji: 15 15.

Tytuł :: Network pharmacology, molecular docking, and in vitro experimental verification of the mechanism of Guanxining in treating diabetic atherosclerosis.
Autorzy :: Wang W; National Clinical Research Center for Chinese Medicine Cardiology, Xiyuan Hospital, Chinese Academy of Chinese Medical Sciences, Beijing, 100091, China.
Wang S; Shandong University of Traditional Chinese Medicine, Jinan, 250014 Shandong China.
Li Y; National Clinical Research Center for Chinese Medicine Cardiology, Xiyuan Hospital, Chinese Academy of Chinese Medical Sciences, Beijing, 100091, China.
Zhu M; National Clinical Research Center for Chinese Medicine Cardiology, Xiyuan Hospital, Chinese Academy of Chinese Medical Sciences, Beijing, 100091, China.
Xu Q; National Clinical Research Center for Chinese Medicine Cardiology, Xiyuan Hospital, Chinese Academy of Chinese Medical Sciences, Beijing, 100091, China.
Luo B; National Clinical Research Center for Chinese Medicine Cardiology, Xiyuan Hospital, Chinese Academy of Chinese Medical Sciences, Beijing, 100091, China.
Liu Y; National Clinical Research Center for Chinese Medicine Cardiology, Xiyuan Hospital, Chinese Academy of Chinese Medical Sciences, Beijing, 100091, China; The Second Department of Gerontology, Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, 100091, China. Electronic address: .
Liu Y; National Clinical Research Center for Chinese Medicine Cardiology, Xiyuan Hospital, Chinese Academy of Chinese Medical Sciences, Beijing, 100091, China. Electronic address: .; Pokaż więcej
Źródło :: Journal of ethnopharmacology [J Ethnopharmacol] 2024 Apr 24; Vol. 324, pp. 117792. Date of Electronic Publication: 2024 Jan 28.
Typ publikacji :: Journal Article
MeSH Terms :: Atherosclerosis*/drug therapy
Drugs, Chinese Herbal*/pharmacology
Drugs, Chinese Herbal*/therapeutic use
Diabetes Mellitus*/drug therapy
Humans ; Molecular Docking Simulation ; Network Pharmacology ; Glucose ; Human Umbilical Vein Endothelial Cells
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Szczegóły

Skocz do pozycji: 16 16.

Tytuł :: Integrated serum metabolomics and network pharmacology analysis on the bioactive metabolites and mechanism exploration of Bufei huoxue capsule on chronic obstructive pulmonary disease rats.
Autorzy :: Ren H; National and Local Collaborative Engineering Center of Chinese Medicinal Resources Industrialization and Formulae Innovative Medicine, Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization and Jiangsu Key Laboratory for High Technology Research of Traditional Chinese Medicine Formulae, Nanjing University of Chinese Medicine, Nanjing, 210023, China.
Wu W; National and Local Collaborative Engineering Center of Chinese Medicinal Resources Industrialization and Formulae Innovative Medicine, Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization and Jiangsu Key Laboratory for High Technology Research of Traditional Chinese Medicine Formulae, Nanjing University of Chinese Medicine, Nanjing, 210023, China.
Chen J; National and Local Collaborative Engineering Center of Chinese Medicinal Resources Industrialization and Formulae Innovative Medicine, Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization and Jiangsu Key Laboratory for High Technology Research of Traditional Chinese Medicine Formulae, Nanjing University of Chinese Medicine, Nanjing, 210023, China.
Li Q; Leiyunshang Pharmaceutical Co. Limited, Suzhou, 215003, China.
Wang H; Leiyunshang Pharmaceutical Co. Limited, Suzhou, 215003, China.
Qian D; National and Local Collaborative Engineering Center of Chinese Medicinal Resources Industrialization and Formulae Innovative Medicine, Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization and Jiangsu Key Laboratory for High Technology Research of Traditional Chinese Medicine Formulae, Nanjing University of Chinese Medicine, Nanjing, 210023, China.
Guo S; National and Local Collaborative Engineering Center of Chinese Medicinal Resources Industrialization and Formulae Innovative Medicine, Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization and Jiangsu Key Laboratory for High Technology Research of Traditional Chinese Medicine Formulae, Nanjing University of Chinese Medicine, Nanjing, 210023, China. Electronic address: .
Duan JA; National and Local Collaborative Engineering Center of Chinese Medicinal Resources Industrialization and Formulae Innovative Medicine, Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization and Jiangsu Key Laboratory for High Technology Research of Traditional Chinese Medicine Formulae, Nanjing University of Chinese Medicine, Nanjing, 210023, China. Electronic address: .; Pokaż więcej
Źródło :: Journal of ethnopharmacology [J Ethnopharmacol] 2024 Apr 24; Vol. 324, pp. 117816. Date of Electronic Publication: 2024 Jan 28.
Typ publikacji :: Journal Article
MeSH Terms :: Pulmonary Disease, Chronic Obstructive*/metabolism
Drugs, Chinese Herbal*/pharmacology
Drugs, Chinese Herbal*/therapeutic use
Medicine, Chinese Traditional*
Rats ; Animals ; Network Pharmacology ; Arachidonic Acid ; Rats, Sprague-Dawley ; Metabolomics/methods ; Laminin
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Szczegóły

Skocz do pozycji: 17 17.

Tytuł :: Mechanistic insights into Qiteng Xiaozhuo Granules' regulation of autophagy for chronic glomerulonephritis treatment: Serum pharmacochemistry, network pharmacology, and experimental validation.
Autorzy :: Liu T; Department of Pharmacy, The First Affiliated Hospital of Anhui University of Chinese Medicine, Hefei, 230012, Anhui, China; College of Pharmacy, Anhui University of Chinese Medicine, Hefei, 230011, Anhui, China. Electronic address: .
Zhuang XX; Department of Pharmacy, Chaohu Hospital of Anhui Medical University, Chaohu, 238000, Anhui, China. Electronic address: .
Tang YY; Department of Pharmacy, The First Affiliated Hospital of Anhui University of Chinese Medicine, Hefei, 230012, Anhui, China; College of Pharmacy, Anhui University of Chinese Medicine, Hefei, 230011, Anhui, China. Electronic address: .
Gao YC; Nephrology, The First Affiliated Hospital of Anhui University of Chinese Medicine, Hefei, 230012, Anhui, China. Electronic address: .
Gao JR; Department of Pharmacy, The First Affiliated Hospital of Anhui University of Chinese Medicine, Hefei, 230012, Anhui, China. Electronic address: .; Pokaż więcej
Źródło :: Journal of ethnopharmacology [J Ethnopharmacol] 2024 Apr 24; Vol. 324, pp. 117819. Date of Electronic Publication: 2024 Jan 28.
Typ publikacji :: Journal Article
MeSH Terms :: Glomerulonephritis*/drug therapy
Drugs, Chinese Herbal*/pharmacology
Drugs, Chinese Herbal*/therapeutic use
Animals ; Mice ; Rats ; Rats, Sprague-Dawley ; Network Pharmacology ; AMP-Activated Protein Kinases ; Molecular Docking Simulation ; Reproducibility of Results ; Autophagy ; Chronic Disease ; TOR Serine-Threonine Kinases
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Szczegóły

Skocz do pozycji: 18 18.

Tytuł :: Exploration the mechanism of Shenling Baizhu San in the treatment of chronic obstructive pulmonary disease based on UPLC-Q-TOF-MS/MS, network pharmacology and in vitro experimental verification.
Autorzy :: Gao Z; College of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Jinan, 250355, PR China.
Wang J; College of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Jinan, 250355, PR China.
Lu G; College of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Jinan, 250355, PR China; Shandong Co-Innovation Center of Classic TCM Formula, Shandong University of Traditional Chinese Medicine, Jinan, 250355, PR China.
Wu Q; College of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Jinan, 250355, PR China.
Wang S; College of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Jinan, 250355, PR China; Shandong Co-Innovation Center of Classic TCM Formula, Shandong University of Traditional Chinese Medicine, Jinan, 250355, PR China.
Wu X; College of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Jinan, 250355, PR China.
Ou C; College of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Jinan, 250355, PR China.
Wu Z; College of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Jinan, 250355, PR China; Shandong Co-Innovation Center of Classic TCM Formula, Shandong University of Traditional Chinese Medicine, Jinan, 250355, PR China.
Yu H; College of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Jinan, 250355, PR China; Shandong Co-Innovation Center of Classic TCM Formula, Shandong University of Traditional Chinese Medicine, Jinan, 250355, PR China.
Wang Y; College of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Jinan, 250355, PR China; Shandong Co-Innovation Center of Classic TCM Formula, Shandong University of Traditional Chinese Medicine, Jinan, 250355, PR China. Electronic address: .; Pokaż więcej
Źródło :: Journal of ethnopharmacology [J Ethnopharmacol] 2024 Apr 24; Vol. 324, pp. 117728. Date of Electronic Publication: 2024 Jan 10.
Typ publikacji :: Journal Article
MeSH Terms :: Drugs, Chinese Herbal*/pharmacology
Drugs, Chinese Herbal*/therapeutic use
Pulmonary Disease, Chronic Obstructive*/drug therapy
Animals ; Rats ; Tandem Mass Spectrometry ; Network Pharmacology ; NF-kappa B ; Chromatography, High Pressure Liquid ; Molecular Docking Simulation ; Toll-Like Receptor 9
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Szczegóły

Skocz do pozycji: 19 19.

Tytuł :: Network pharmacology mechanisms and experimental verification of licorice in the treatment of ulcerative colitis.
Autorzy :: Kong J; School of Pharmacy, Anhui University of Chinese Medicine, Hefei City, Anhui Province, China; Anhui Province Key Laboratory of Chinese Medicinal Formula, Hefei City, Anhui Province, China.
Xiang Q; School of Pharmacy, Anhui University of Chinese Medicine, Hefei City, Anhui Province, China; Anhui Province Key Laboratory of Chinese Medicinal Formula, Hefei City, Anhui Province, China.
Ge W; School of Pharmacy, Anhui University of Chinese Medicine, Hefei City, Anhui Province, China; Anhui Province Key Laboratory of Chinese Medicinal Formula, Hefei City, Anhui Province, China.
Wang Y; School of Pharmacy, Anhui University of Chinese Medicine, Hefei City, Anhui Province, China; Anhui Province Key Laboratory of Chinese Medicinal Formula, Hefei City, Anhui Province, China.
Xu F; School of Pharmacy, Anhui University of Chinese Medicine, Hefei City, Anhui Province, China; Anhui Province Key Laboratory of Chinese Medicinal Formula, Hefei City, Anhui Province, China. Electronic address: .
Shi G; School of Pharmacy, Anhui University of Chinese Medicine, Hefei City, Anhui Province, China; Anhui Province Key Laboratory of Chinese Medicinal Formula, Hefei City, Anhui Province, China. Electronic address: .; Pokaż więcej
Źródło :: Journal of ethnopharmacology [J Ethnopharmacol] 2024 Apr 24; Vol. 324, pp. 117691. Date of Electronic Publication: 2024 Jan 02.
Typ publikacji :: Journal Article
MeSH Terms :: Colitis, Ulcerative*/chemically induced
Colitis, Ulcerative*/drug therapy
Colitis, Ulcerative*/metabolism
Glycyrrhiza*
Glycyrrhetinic Acid*/pharmacology
Colitis*/drug therapy
Humans ; Animals ; Mice ; Interleukin-17/metabolism ; Colon ; Network Pharmacology ; Caco-2 Cells ; Lipopolysaccharides/toxicity ; NF-E2-Related Factor 2/metabolism ; Interleukin-6/metabolism ; Molecular Docking Simulation ; Occludin/metabolism ; Inflammation/pathology ; Ubiquitin-Protein Ligases/metabolism ; Protein Kinases/metabolism ; Dextran Sulfate/toxicity ; Disease Models, Animal ; Mice, Inbred C57BL
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Szczegóły

Skocz do pozycji: 20 20.

Tytuł :: 1-Ethoxycarbonyl-beta-carboline inhibits the M2 polarization of tumor-associated macrophages: A study based on network pharmacology and molecular docking analyses.
Autorzy :: Cao C; The Second Affiliated Hospital of Jiaxing University, 314001, China.
Sheng J; The Second Affiliated Hospital of Jiaxing University, 314001, China.
Wang J; The Second Affiliated Hospital of Jiaxing University, 314001, China.
Zhou X; The Second Affiliated Hospital of Jiaxing University, 314001, China.
Li W; The Second Affiliated Hospital of Jiaxing University, 314001, China.
Kong Y; The Second Affiliated Hospital of Jiaxing University, 314001, China.
Zhang C; The Second Affiliated Hospital of Jiaxing University, 314001, China. Electronic address: caiqun_.; Pokaż więcej
Źródło :: International immunopharmacology [Int Immunopharmacol] 2024 Apr 20; Vol. 131, pp. 111907. Date of Electronic Publication: 2024 Mar 22.
Typ publikacji :: Journal Article
MeSH Terms :: Tumor-Associated Macrophages*/metabolism
Network Pharmacology*
Animals ; Mice ; Molecular Docking Simulation ; Cytokines/metabolism ; Carbolines/pharmacology ; Carbolines/therapeutic use
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