Temat: "Agonist" - Prolib Integro

Skocz do pozycji: 1 1.

Tytuł :: BCL-2-family protein tBID can act as a BAX-like effector of apoptosis.
Autorzy :: Flores-Romero H; Institute for Genetics, University of Cologne, Cologne, Germany.; Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Cologne, Germany.; Interfaculty Institute of Biochemistry, Eberhard-Karls-Universität Tübingen, Tübingen, Germany.
Hohorst L; Institute for Genetics, University of Cologne, Cologne, Germany.; Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Cologne, Germany.
John M; Interfaculty Institute of Biochemistry, Eberhard-Karls-Universität Tübingen, Tübingen, Germany.
Albert MC; Institute for Molecular Immunology, and Center for Molecular Medicine Cologne (CMMC), Faculty of Medicine, University Hospital of Cologne, University of Cologne, Cologne, Germany.
King LE; Institute for Genetics, University of Cologne, Cologne, Germany.; Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Cologne, Germany.
Beckmann L; Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Cologne, Germany.; Department I of Internal Medicine, University Hospital of Cologne, Cologne, Germany.; Center of Integrated Oncology ABCD, University Hospital of Cologne, Cologne, Germany.
Szabo T; Division of Developmental Immunology, Biocenter, Medical University of Innsbruck, Innsbruck, Austria.
Hertlein V; Interfaculty Institute of Biochemistry, Eberhard-Karls-Universität Tübingen, Tübingen, Germany.
Luo X; Eppley Institute for Research in Cancer and Allied Diseases, Fred & Pamela Buffett Cancer Center, University of Nebraska Medical Center, Omaha, ME, USA.; Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE, USA.
Villunger A; Division of Developmental Immunology, Biocenter, Medical University of Innsbruck, Innsbruck, Austria.; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria.; Ludwig Boltzmann Institute for Rare and Undiagnosed Diseases, Vienna, Austria.
Frenzel LP; Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Cologne, Germany.; Department I of Internal Medicine, University Hospital of Cologne, Cologne, Germany.; Center of Integrated Oncology ABCD, University Hospital of Cologne, Cologne, Germany.
Kashkar H; Institute for Molecular Immunology, and Center for Molecular Medicine Cologne (CMMC), Faculty of Medicine, University Hospital of Cologne, University of Cologne, Cologne, Germany.
Garcia-Saez AJ; Institute for Genetics, University of Cologne, Cologne, Germany.; Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Cologne, Germany.; Interfaculty Institute of Biochemistry, Eberhard-Karls-Universität Tübingen, Tübingen, Germany.; Pokaż więcej
Źródło :: The EMBO journal [EMBO J] 2022 Dec 17; Vol. 41 (2), pp. e108690. Date of Electronic Publication: 2021 Dec 21.
Typ publikacji :: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :: Apoptosis*
BH3 Interacting Domain Death Agonist Protein/*metabolism
Apoptosis Regulatory Proteins/metabolism ; BH3 Interacting Domain Death Agonist Protein/chemistry ; BH3 Interacting Domain Death Agonist Protein/genetics ; HCT116 Cells ; HeLa Cells ; Humans ; Mitochondria/metabolism ; Mitochondrial Proteins/metabolism ; Protein Domains ; Proteolysis ; Proto-Oncogene Proteins c-bcl-2/metabolism ; bcl-2 Homologous Antagonist-Killer Protein/metabolism ; bcl-2-Associated X Protein/metabolism
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 2 2.

Tytuł :: The BCL-2 family member BID plays a role during embryonic development in addition to its BH3-only protein function by acting in parallel to BAX, BAK and BOK.
Autorzy :: Ke FS; The Walter and Eliza Hall Institute of Medical Research (WEHI), Melbourne, Vic, Australia.; Department of Medical Biology, University of Melbourne, Melbourne, Vic, Australia.
Holloway S; The Walter and Eliza Hall Institute of Medical Research (WEHI), Melbourne, Vic, Australia.
Uren RT; The Walter and Eliza Hall Institute of Medical Research (WEHI), Melbourne, Vic, Australia.; Department of Medical Biology, University of Melbourne, Melbourne, Vic, Australia.
Wong AW; The Walter and Eliza Hall Institute of Medical Research (WEHI), Melbourne, Vic, Australia.
Little MH; Department of Paediatrics, University of Melbourne, Melbourne, Vic, Australia.; Murdoch Children's Medical Research Institute, Melbourne, Vic, Australia.
Kluck RM; The Walter and Eliza Hall Institute of Medical Research (WEHI), Melbourne, Vic, Australia.; Department of Medical Biology, University of Melbourne, Melbourne, Vic, Australia.
Voss AK; The Walter and Eliza Hall Institute of Medical Research (WEHI), Melbourne, Vic, Australia.; Department of Medical Biology, University of Melbourne, Melbourne, Vic, Australia.
Strasser A; The Walter and Eliza Hall Institute of Medical Research (WEHI), Melbourne, Vic, Australia.; Department of Medical Biology, University of Melbourne, Melbourne, Vic, Australia.; Pokaż więcej
Źródło :: The EMBO journal [EMBO J] 2022 Aug 01; Vol. 41 (15), pp. e110300. Date of Electronic Publication: 2022 Jun 27.
Typ publikacji :: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :: bcl-2 Homologous Antagonist-Killer Protein*/genetics
bcl-2 Homologous Antagonist-Killer Protein*/metabolism
BH3 Interacting Domain Death Agonist Protein*/genetics
BH3 Interacting Domain Death Agonist Protein*/metabolism
Proto-Oncogene Proteins c-bcl-2*/genetics
Proto-Oncogene Proteins c-bcl-2*/metabolism
Animals ; Mice ; Apoptosis ; bcl-2-Associated X Protein/genetics ; bcl-2-Associated X Protein/metabolism ; Embryonic Development/genetics ; Mice, Knockout
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 3 3.

Tytuł :: Crystal structure of Bak bound to the BH3 domain of Bnip5, a noncanonical BH3 domain-containing protein.
Autorzy :: Lim D; Disease Target Structure Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, Republic of Korea.; Critical Diseases Diagnostics Convergence Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, Republic of Korea.; Department of Biochemistry, Chungnam National University, Daejeon, Republic of Korea.
Jeong DE; Disease Target Structure Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, Republic of Korea.; Critical Diseases Diagnostics Convergence Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, Republic of Korea.; Department of Biology, Chungnam National University, Daejeon, Republic of Korea.
Shin HC; Critical Diseases Diagnostics Convergence Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, Republic of Korea.
Choi JS; Department of Biochemistry, Chungnam National University, Daejeon, Republic of Korea.
Seo J; Aging Convergence Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, Republic of Korea.
Kim SJ; Disease Target Structure Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, Republic of Korea.; Critical Diseases Diagnostics Convergence Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, Republic of Korea.
Ku B; Disease Target Structure Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, Republic of Korea.; Pokaż więcej
Źródło :: Proteins [Proteins] 2024 Jan; Vol. 92 (1), pp. 44-51. Date of Electronic Publication: 2023 Aug 08.
Typ publikacji :: Journal Article
MeSH Terms :: Proto-Oncogene Proteins c-bcl-2*/chemistry
bcl-2 Homologous Antagonist-Killer Protein*/chemistry
bcl-2 Homologous Antagonist-Killer Protein*/metabolism
Protein Domains ; bcl-X Protein/metabolism ; BH3 Interacting Domain Death Agonist Protein/metabolism ; Apoptosis/physiology
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 4 4.

Tytuł :: Design BH3 domain fusion protein as targeting pro-apoptotic self-assembling nanoparticles.
Autorzy :: Shuai Z; Department of Biopharmaceutics, West China School of Pharmacy, Sichuan University, No. 17, Renmin Road, Chengdu 610041, Sichuan Province, PR China; Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry, Sichuan Engineering Laboratory for Plant-Sourced Drug and Sichuan Research Center for Drug Precision Industrial Technology, West China School of Pharmacy Sichuan University, Chengdu 610041 PR China.
Zheng Y; Department of Biopharmaceutics, West China School of Pharmacy, Sichuan University, No. 17, Renmin Road, Chengdu 610041, Sichuan Province, PR China; Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry, Sichuan Engineering Laboratory for Plant-Sourced Drug and Sichuan Research Center for Drug Precision Industrial Technology, West China School of Pharmacy Sichuan University, Chengdu 610041 PR China.
Jiang J; Department of Biopharmaceutics, West China School of Pharmacy, Sichuan University, No. 17, Renmin Road, Chengdu 610041, Sichuan Province, PR China; Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry, Sichuan Engineering Laboratory for Plant-Sourced Drug and Sichuan Research Center for Drug Precision Industrial Technology, West China School of Pharmacy Sichuan University, Chengdu 610041 PR China.
Yu R; Department of Biopharmaceutics, West China School of Pharmacy, Sichuan University, No. 17, Renmin Road, Chengdu 610041, Sichuan Province, PR China; Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry, Sichuan Engineering Laboratory for Plant-Sourced Drug and Sichuan Research Center for Drug Precision Industrial Technology, West China School of Pharmacy Sichuan University, Chengdu 610041 PR China.
Zhang C; Department of Biopharmaceutics, West China School of Pharmacy, Sichuan University, No. 17, Renmin Road, Chengdu 610041, Sichuan Province, PR China; Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry, Sichuan Engineering Laboratory for Plant-Sourced Drug and Sichuan Research Center for Drug Precision Industrial Technology, West China School of Pharmacy Sichuan University, Chengdu 610041 PR China. Electronic address: .; Pokaż więcej
Źródło :: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2021 Sep; Vol. 141, pp. 111825. Date of Electronic Publication: 2021 Jun 18.
Typ publikacji :: Journal Article
MeSH Terms :: Antineoplastic Agents/*pharmacology
Apoptosis/*drug effects
BH3 Interacting Domain Death Agonist Protein/*pharmacology
Neoplasms/*drug therapy
Animals ; Antineoplastic Agents/chemistry ; Antineoplastic Agents/therapeutic use ; Apoptosis Regulatory Proteins ; BH3 Interacting Domain Death Agonist Protein/chemistry ; BH3 Interacting Domain Death Agonist Protein/therapeutic use ; Cell Line, Tumor ; Cell Survival/drug effects ; Female ; Ferritins/chemistry ; Humans ; MCF-7 Cells ; Mice ; Nanoparticles ; Particle Size
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 5 5.

Tytuł :: Structural basis for proapoptotic activation of Bak by the noncanonical BH3-only protein Pxt1.
Autorzy :: Lim D; Disease Target Structure Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, Korea.; Critical Diseases Diagnostics Convergence Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, Korea.; Department of Biochemistry, Chungnam National University, Daejeon, Korea.
Choe SH; Aging Convergence Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, Korea.
Jin S; Aging Convergence Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, Korea.
Lee S; Department of Biochemistry, Chungnam National University, Daejeon, Korea.
Kim Y; Department of Biochemistry, Chungnam National University, Daejeon, Korea.
Shin HC; Critical Diseases Diagnostics Convergence Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, Korea.
Choi JS; Department of Biochemistry, Chungnam National University, Daejeon, Korea.
Oh DB; Aging Convergence Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, Korea.; Department of Biosystems and Bioengineering, KRIBB School of Biotechnology, University of Science and Technology, Daejeon, Korea.
Kim SJ; Disease Target Structure Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, Korea.; Critical Diseases Diagnostics Convergence Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, Korea.; Department of Proteome Structural Biology, KRIBB School of Bioscience, University of Science and Technology, Daejeon, Korea.
Seo J; Aging Convergence Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, Korea.; Department of Biosystems and Bioengineering, KRIBB School of Biotechnology, University of Science and Technology, Daejeon, Korea.
Ku B; Disease Target Structure Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, Korea.; Department of Proteome Structural Biology, KRIBB School of Bioscience, University of Science and Technology, Daejeon, Korea.; Pokaż więcej
Źródło :: PLoS biology [PLoS Biol] 2023 Jun 14; Vol. 21 (6), pp. e3002156. Date of Electronic Publication: 2023 Jun 14 (Print Publication: 2023).
Typ publikacji :: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
MeSH Terms :: Proto-Oncogene Proteins c-bcl-2*
Humans ; Male ; Apoptosis/physiology ; bcl-2-Associated X Protein ; BH3 Interacting Domain Death Agonist Protein/metabolism ; Carrier Proteins/metabolism ; Mitochondria/metabolism
: Czasopismo naukowe

Szczegóły Pełny tekst Pełny tekst

Skocz do pozycji: 6 6.

Tytuł :: Direct Measurement of the Affinity between tBid and Bax in a Mitochondria-Like Membrane.
Autorzy :: Rose M; Department of Physics and Astronomy, McMaster University, Hamilton, ON L8S 4M1, Canada.
Kurylowicz M; Department of Physics and Astronomy, McMaster University, Hamilton, ON L8S 4M1, Canada.
Mahmood M; Department of Physics and Astronomy, McMaster University, Hamilton, ON L8S 4M1, Canada.
Winkel S; Department of Physics and Astronomy, McMaster University, Hamilton, ON L8S 4M1, Canada.
Moran-Mirabal JM; Department of Chemistry and Chemical Biology, McMaster University, Hamilton, ON L8S 4M1, Canada.
Fradin C; Department of Physics and Astronomy, McMaster University, Hamilton, ON L8S 4M1, Canada.; Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, ON L8S 4K1, Canada.; Pokaż więcej
Źródło :: International journal of molecular sciences [Int J Mol Sci] 2021 Jul 31; Vol. 22 (15). Date of Electronic Publication: 2021 Jul 31.
Typ publikacji :: Journal Article
MeSH Terms :: BH3 Interacting Domain Death Agonist Protein/*chemistry
Lipid Bilayers/*chemistry
bcl-2-Associated X Protein/*chemistry
Animals ; BH3 Interacting Domain Death Agonist Protein/metabolism ; Humans ; Lipid Bilayers/metabolism ; Mice ; Protein Binding ; Protein Conformation ; bcl-2-Associated X Protein/metabolism
: Czasopismo naukowe

Szczegóły Pełny tekst Pełny tekst

Skocz do pozycji: 7 7.

Tytuł :: Apoptotic mitochondrial poration by a growing list of pore-forming BCL-2 family proteins.
Autorzy :: Moldoveanu T; Department of Biochemistry and Molecular Biology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.; Pokaż więcej
Źródło :: BioEssays : news and reviews in molecular, cellular and developmental biology [Bioessays] 2023 Mar; Vol. 45 (3), pp. e2200221. Date of Electronic Publication: 2023 Jan 17.
Typ publikacji :: Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :: Mitochondria*/metabolism
Apoptosis*/physiology
bcl-2-Associated X Protein/metabolism ; BH3 Interacting Domain Death Agonist Protein/genetics ; BH3 Interacting Domain Death Agonist Protein/metabolism
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 8 8.

Tytuł :: Bid is involved in apoptosis induced by Chinese giant salamander iridovirus and contributes to the viral replication in an amphibian cell line.
Autorzy :: Li Y; Yangtze River Fisheries Research Institute, Chinese Academy of Fishery Sciences, Wuhan, 430223, China.
Liu Y; Yangtze River Fisheries Research Institute, Chinese Academy of Fishery Sciences, Wuhan, 430223, China.
Zhou Y; Yangtze River Fisheries Research Institute, Chinese Academy of Fishery Sciences, Wuhan, 430223, China.
Liu W; Yangtze River Fisheries Research Institute, Chinese Academy of Fishery Sciences, Wuhan, 430223, China.
Fan Y; Yangtze River Fisheries Research Institute, Chinese Academy of Fishery Sciences, Wuhan, 430223, China.
Jiang N; Yangtze River Fisheries Research Institute, Chinese Academy of Fishery Sciences, Wuhan, 430223, China.
Xue M; Yangtze River Fisheries Research Institute, Chinese Academy of Fishery Sciences, Wuhan, 430223, China.
Meng Y; Yangtze River Fisheries Research Institute, Chinese Academy of Fishery Sciences, Wuhan, 430223, China.
Zeng L; Yangtze River Fisheries Research Institute, Chinese Academy of Fishery Sciences, Wuhan, 430223, China. Electronic address: .; Pokaż więcej
Źródło :: Developmental and comparative immunology [Dev Comp Immunol] 2021 Mar; Vol. 116, pp. 103935. Date of Electronic Publication: 2020 Nov 23.
Typ publikacji :: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :: Apoptosis*
Virus Replication*
BH3 Interacting Domain Death Agonist Protein/*metabolism
Iridoviridae/*physiology
Urodela/*virology
Amphibian Proteins/genetics ; Amphibian Proteins/metabolism ; Animals ; BH3 Interacting Domain Death Agonist Protein/genetics ; Capsid Proteins/genetics ; Capsid Proteins/metabolism ; Cell Line ; Cytopathogenic Effect, Viral ; DNA Virus Infections/metabolism ; DNA Virus Infections/pathology ; DNA Virus Infections/veterinary ; DNA Virus Infections/virology ; Gene Expression ; Phylogeny ; Sequence Analysis ; Urodela/classification ; Urodela/genetics
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 9 9.

Tytuł :: The Bcl-2 family protein bid interacts with the ER stress sensor IRE1 to differentially modulate its RNase activity.
Autorzy :: Bashir S; Department of Biotechnology, University of Kashmir, Hazratbal J&K, India.
Banday M; Department of Biotechnology, University of Kashmir, Hazratbal J&K, India.
Qadri O; Department of Biotechnology, University of Kashmir, Hazratbal J&K, India.
Pal D; Department of Computational and Data Science (CDS), Indian Institute of Science (IISc), Bengaluru, India.
Bashir A; Department of Biotechnology, University of Kashmir, Hazratbal J&K, India.
Hilal N; Department of Biotechnology, University of Kashmir, Hazratbal J&K, India.
Altaf M; Department of Biotechnology, University of Kashmir, Hazratbal J&K, India.
Fazili KM; Department of Biotechnology, University of Kashmir, Hazratbal J&K, India.; Pokaż więcej
Źródło :: FEBS letters [FEBS Lett] 2023 Apr; Vol. 597 (7), pp. 962-974. Date of Electronic Publication: 2023 Feb 16.
Typ publikacji :: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :: Protein Serine-Threonine Kinases*/genetics
Protein Serine-Threonine Kinases*/metabolism
Unfolded Protein Response*
Endoplasmic Reticulum Stress/physiology ; Endoribonucleases/genetics ; Endoribonucleases/metabolism ; Membrane Proteins/metabolism ; Ribonucleases/metabolism ; X-Box Binding Protein 1/genetics ; X-Box Binding Protein 1/metabolism ; BH3 Interacting Domain Death Agonist Protein/metabolism
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 10 10.

Tytuł :: Effect of UV Stress on the Structure and Function of Pro-apoptotic Bid and Anti-apoptotic Bcl-xl proteins.
Autorzy :: Bera A; Department of Biophysics, University of Mumbai Santacruz (E) Kalina, Mumbai, 400101, India.
Singh S; Department of Biophysics, University of Mumbai Santacruz (E) Kalina, Mumbai, 400101, India.
D'Souza JS; Department of Biology, UM-DAE Centre for Excellence in Basic Sciences Santacruz (E) Kalina, Mumbai, 400101, India.
Hosur RV; Department of Biology, UM-DAE Centre for Excellence in Basic Sciences Santacruz (E) Kalina, Mumbai, 400101, India.
Mishra P; Department of Biophysics, University of Mumbai Santacruz (E) Kalina, Mumbai, 400101, India.; Pokaż więcej
Źródło :: Chembiochem : a European journal of chemical biology [Chembiochem] 2023 Mar 01; Vol. 24 (5), pp. e202200682. Date of Electronic Publication: 2023 Feb 03.
Typ publikacji :: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :: Apoptosis Regulatory Proteins*
Apoptosis*
Animals ; bcl-X Protein/metabolism ; BH3 Interacting Domain Death Agonist Protein/metabolism ; Mitochondria/metabolism ; Proto-Oncogene Proteins c-bcl-2/metabolism ; Mammals/metabolism
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 11 11.

Tytuł :: Humanin selectively prevents the activation of pro-apoptotic protein BID by sequestering it into fibers.
Autorzy :: Morris DL; Laboratory of Molecular Biophysics, Biochemistry and Biophysics Center, NHLBI, National Institutes of Health, Bethesda, Maryland, USA.
Johnson S; Laboratory of Molecular Biophysics, Biochemistry and Biophysics Center, NHLBI, National Institutes of Health, Bethesda, Maryland, USA.
Bleck CKE; Electron Microscopy Core Facility, NHLBI, National Institutes of Health, Bethesda, Maryland, USA.
Lee DY; Biochemistry Core Facility, NHLBI, National Institutes of Health, Bethesda, Maryland, USA.
Tjandra N; Laboratory of Molecular Biophysics, Biochemistry and Biophysics Center, NHLBI, National Institutes of Health, Bethesda, Maryland, USA. Electronic address: .; Pokaż więcej
Źródło :: The Journal of biological chemistry [J Biol Chem] 2020 Dec 25; Vol. 295 (52), pp. 18226-18238. Date of Electronic Publication: 2020 Oct 26.
Typ publikacji :: Journal Article; Research Support, N.I.H., Intramural
MeSH Terms :: BH3 Interacting Domain Death Agonist Protein/*chemistry
Intracellular Signaling Peptides and Proteins/*metabolism
Proto-Oncogene Proteins c-bcl-2/*chemistry
bcl-2-Associated X Protein/*chemistry
bcl-X Protein/*chemistry
Amino Acid Sequence ; BH3 Interacting Domain Death Agonist Protein/metabolism ; Humans ; Intracellular Signaling Peptides and Proteins/genetics ; Mitochondrial Membranes/metabolism ; Mutation ; Protein Conformation ; Proto-Oncogene Proteins c-bcl-2/metabolism ; bcl-2-Associated X Protein/metabolism ; bcl-X Protein/metabolism
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 12 12.

Tytuł :: Involvement of Bid in the crosstalk between ferroptotic agent-induced ER stress and TRAIL-induced apoptosis.
Autorzy :: Kim JH; Department of Surgery, UPMC Hillman Cancer Center, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Najy AJ; Department of Pathology, Barbara Ann Karmanos Institute, Wayne State University School of Medicine, Detroit, Michigan, USA.; Department of Oncology, Barbara Ann Karmanos Institute, Wayne State University School of Medicine, Detroit, Michigan, USA.
Li J; Eppley Institute for Research in Cancer and Allied Diseases, Fred and Pamela Buffett Cancer Center, University of Nebraska Medical Center, Omaha, Nebraska, USA.
Luo X; Eppley Institute for Research in Cancer and Allied Diseases, Fred and Pamela Buffett Cancer Center, University of Nebraska Medical Center, Omaha, Nebraska, USA.
Kim HC; Department of Pathology, Barbara Ann Karmanos Institute, Wayne State University School of Medicine, Detroit, Michigan, USA.; Department of Oncology, Barbara Ann Karmanos Institute, Wayne State University School of Medicine, Detroit, Michigan, USA.
Choudry MHA; Department of Surgery, UPMC Hillman Cancer Center, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Lee YJ; Department of Surgery, UPMC Hillman Cancer Center, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.; Pokaż więcej
Źródło :: Journal of cellular physiology [J Cell Physiol] 2022 Nov; Vol. 237 (11), pp. 4180-4196. Date of Electronic Publication: 2022 Aug 22.
Typ publikacji :: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, N.I.H., Extramural
MeSH Terms :: Apoptosis*
Ovarian Neoplasms*/pathology
Humans ; Female ; Cell Line, Tumor ; TNF-Related Apoptosis-Inducing Ligand/pharmacology ; TNF-Related Apoptosis-Inducing Ligand/metabolism ; BH3 Interacting Domain Death Agonist Protein/genetics ; BH3 Interacting Domain Death Agonist Protein/metabolism ; Caspase 8/metabolism ; Endoplasmic Reticulum Stress ; Tumor Necrosis Factor-alpha/metabolism
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 13 13.

Tytuł :: Subcutaneously administered tirzepatide vs semaglutide for adults with type 2 diabetes: a systematic review and network meta-analysis of randomised controlled trials
Autorzy :: Karagiannis, ThomasAff1, Aff2, IDs00125024061441_cor1
Malandris, Konstantinos
Avgerinos, IoannisAff1, Aff2
Stamati, Athina
Kakotrichi, Panagiota
Liakos, ArisAff1, Aff2
Vasilakou, DespoinaAff1, Aff2
Kakaletsis, Nikolaos
Tsapas, ApostolosAff1, Aff2, Aff4
Bekiari, EleniAff1, Aff2; Pokaż więcej
Źródło :: Diabetologia: Clinical, Translational and Experimental Diabetes and Metabolism. :1-17
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 14 14.

Tytuł :: Liver-specific Bid silencing inhibits APAP-induced cell death in mice.
Autorzy :: Maxa M; Institute for Experimental Surgery, Rostock University Medical Center, Schillingallee 69a, 18057, Rostock, Germany.
Schaeper U; Silence Therapeutics GmbH, Berlin, Germany.
Dames S; Silence Therapeutics GmbH, Berlin, Germany.
Vollmar B; Institute for Experimental Surgery, Rostock University Medical Center, Schillingallee 69a, 18057, Rostock, Germany.
Kuhla A; Institute for Experimental Surgery, Rostock University Medical Center, Schillingallee 69a, 18057, Rostock, Germany. .; Pokaż więcej
Źródło :: Apoptosis : an international journal on programmed cell death [Apoptosis] 2019 Dec; Vol. 24 (11-12), pp. 934-945.
Typ publikacji :: Journal Article
MeSH Terms :: Acetaminophen/*toxicity
Apoptosis/*genetics
BH3 Interacting Domain Death Agonist Protein/*metabolism
Chemical and Drug Induced Liver Injury/*metabolism
Hepatocytes/*metabolism
Liver Failure, Acute/*chemically induced
Animals ; BH3 Interacting Domain Death Agonist Protein/genetics ; Chemical and Drug Induced Liver Injury/enzymology ; Chemical and Drug Induced Liver Injury/genetics ; Cytochrome P450 Family 2/metabolism ; Glutathione/metabolism ; HMGB1 Protein/metabolism ; Hepatocytes/pathology ; Inflammation/complications ; Inflammation/metabolism ; Liver/enzymology ; Liver/metabolism ; Liver/pathology ; Liver Failure, Acute/enzymology ; Liver Failure, Acute/metabolism ; Male ; Mice ; Mice, Inbred C57BL ; Necrosis/metabolism ; RNA Interference ; RNA, Small Interfering/genetics ; RNA, Small Interfering/metabolism ; bcl-2-Associated X Protein/metabolism
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 15 15.

Tytuł :: Polyethyleneimine-polyethylene glycol copolymer targeted by anti-HER2 nanobody for specific delivery of transcriptionally targeted tBid containing construct.
Autorzy :: Saqafi B; a Faculty of Medical Sciences, Department of Medical Biotechnology , Tarbiat Modares University , Tehran , Iran.
Rahbarizadeh F; a Faculty of Medical Sciences, Department of Medical Biotechnology , Tarbiat Modares University , Tehran , Iran.; Pokaż więcej
Źródło :: Artificial cells, nanomedicine, and biotechnology [Artif Cells Nanomed Biotechnol] 2019 Dec; Vol. 47 (1), pp. 501-511.
Typ publikacji :: Journal Article
MeSH Terms :: Antineoplastic Agents, Immunological*/chemistry
Antineoplastic Agents, Immunological*/pharmacology
BH3 Interacting Domain Death Agonist Protein*/biosynthesis
BH3 Interacting Domain Death Agonist Protein*/genetics
Gene Transfer Techniques*
Genetic Therapy*
Polyethylene Glycols*/chemistry
Polyethylene Glycols*/pharmacology
Single-Domain Antibodies*/chemistry
Single-Domain Antibodies*/pharmacology
Polyethyleneimine/*analogs & derivatives
Receptor, ErbB-2/*antagonists & inhibitors
Transcription, Genetic/*drug effects
Breast Neoplasms/genetics ; Breast Neoplasms/metabolism ; Breast Neoplasms/therapy ; Female ; Humans ; Polyethyleneimine/chemistry ; Polyethyleneimine/pharmacology ; Receptor, ErbB-2/genetics ; Receptor, ErbB-2/metabolism
: Czasopismo naukowe

Szczegóły Pełny tekst

Skocz do pozycji: 16 16.

Tytuł :: Design, synthesis and anti-tumor activity studies of novel pyrido[3, 4-d]pyrimidine derivatives.
Autorzy :: Guo WG; State Key Laboratory of Esophageal Cancer Prevention and Treatment, Key Laboratory of Advanced Pharmaceutical Technology, Ministry of Education of China, School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450001, China; Pharmaceutical Department, Changzhi Medical College, Changzhi 046000, China.
Zhao JR; State Key Laboratory of Esophageal Cancer Prevention and Treatment, Key Laboratory of Advanced Pharmaceutical Technology, Ministry of Education of China, School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450001, China.
Li M; State Key Laboratory of Esophageal Cancer Prevention and Treatment, Key Laboratory of Advanced Pharmaceutical Technology, Ministry of Education of China, School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450001, China.
Hu T; State Key Laboratory of Esophageal Cancer Prevention and Treatment, Key Laboratory of Advanced Pharmaceutical Technology, Ministry of Education of China, School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450001, China.
Dan Z; State Key Laboratory of Esophageal Cancer Prevention and Treatment, Key Laboratory of Advanced Pharmaceutical Technology, Ministry of Education of China, School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450001, China.
Zhang Q; State Key Laboratory of Esophageal Cancer Prevention and Treatment, Key Laboratory of Advanced Pharmaceutical Technology, Ministry of Education of China, School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450001, China.
Ma LY; State Key Laboratory of Esophageal Cancer Prevention and Treatment, Key Laboratory of Advanced Pharmaceutical Technology, Ministry of Education of China, School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450001, China; China Meheco Topfond Pharmaceutical Co., Zhumadian 463000, China; Laboratory of Cardio-cerebrovascular Drug, Henan Province, China. Electronic address: .
Zhang SY; School of Basic Medical Science, Zhengzhou University, Zhengzhou 450001, China. Electronic address: .
Zhao B; State Key Laboratory of Esophageal Cancer Prevention and Treatment, Key Laboratory of Advanced Pharmaceutical Technology, Ministry of Education of China, School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450001, China. Electronic address: .; Pokaż więcej
Źródło :: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2022 Nov 15; Vol. 76, pp. 129020. Date of Electronic Publication: 2022 Oct 08.
Typ publikacji :: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :: Antineoplastic Agents*/chemical synthesis
Antineoplastic Agents*/pharmacology
Pyrimidines*/chemical synthesis
Pyrimidines*/pharmacology
Apoptosis*/drug effects
Humans ; Structure-Activity Relationship ; Poly(ADP-ribose) Polymerases/metabolism ; BH3 Interacting Domain Death Agonist Protein/metabolism ; Cell Line, Tumor
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 17 17.

Tytuł :: Ca Influence the Thermodynamics of Peptide-Membrane Interactions.
Autorzy :: Vasquez-Montes V; Department of Biochemistry and Molecular Biology, The University of Kansas Medical Center, Kansas City, KS 66160, United States.
Goldberg AFX; Eye Research Institute, Oakland University, Rochester, MI 48309, United States.
Thévenin D; Department of Chemistry, Lehigh University, Bethlehem, PA 18015, United States. Electronic address: https://twitter.com/TheveninLab.
Ladokhin AS; Department of Biochemistry and Molecular Biology, The University of Kansas Medical Center, Kansas City, KS 66160, United States. Electronic address: .; Pokaż więcej
Źródło :: Journal of molecular biology [J Mol Biol] 2022 Nov 15; Vol. 434 (21), pp. 167826. Date of Electronic Publication: 2022 Sep 14.
Typ publikacji :: Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :: Lipid Bilayers*/chemistry
Peptides*/chemistry
Calcium*/chemistry
Magnesium*/chemistry
Hydrogen-Ion Concentration ; Spectrometry, Fluorescence ; Thermodynamics ; BH3 Interacting Domain Death Agonist Protein/chemistry ; Peripherins/chemistry
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 18 18.

Tytuł :: Caspase-1 cleaves Bid to release mitochondrial SMAC and drive secondary necrosis in the absence of GSDMD.
Autorzy :: Heilig R; Department of Biochemistry, University of Lausanne, Epalinges, Switzerland.
Dilucca M; Department of Biochemistry, University of Lausanne, Epalinges, Switzerland.
Boucher D; Department of Biochemistry, University of Lausanne, Epalinges, Switzerland.
Chen KW; Department of Biochemistry, University of Lausanne, Epalinges, Switzerland.
Hancz D; Department of Biochemistry, University of Lausanne, Epalinges, Switzerland.
Demarco B; Department of Biochemistry, University of Lausanne, Epalinges, Switzerland.
Shkarina K; Department of Biochemistry, University of Lausanne, Epalinges, Switzerland.
Broz P; Department of Biochemistry, University of Lausanne, Epalinges, Switzerland .; Pokaż więcej
Źródło :: Life science alliance [Life Sci Alliance] 2020 Apr 28; Vol. 3 (6). Date of Electronic Publication: 2020 Apr 28 (Print Publication: 2020).
Typ publikacji :: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :: Apoptosis Regulatory Proteins/*metabolism
BH3 Interacting Domain Death Agonist Protein/*deficiency
Caspase 1/*deficiency
Intracellular Signaling Peptides and Proteins/*deficiency
Mitochondria/*metabolism
Mitochondrial Proteins/*metabolism
Phosphate-Binding Proteins/*deficiency
Signal Transduction/*genetics
Animals ; Apoptosis/genetics ; BH3 Interacting Domain Death Agonist Protein/genetics ; Caspase 1/genetics ; Cells, Cultured ; Gene Editing ; Gene Knockout Techniques ; Inflammasomes/metabolism ; Intracellular Signaling Peptides and Proteins/genetics ; Macrophages/metabolism ; Macrophages/pathology ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Mitochondrial Membranes/metabolism ; Necrosis/genetics ; Necrosis/metabolism ; Phosphate-Binding Proteins/genetics ; Pyroptosis/genetics ; Transfection
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 19 19.

Tytuł :: Truncated Bid Regulates Cisplatin Response via Activation of Mitochondrial Apoptosis Pathway in Ovarian Cancer.
Autorzy :: Dai Y; Cancer Biology Research Center (Key Laboratory of the Ministry of Education), Tongji Medical College, Huazhong University of Science and Technology, Tongji Hospital, Wuhan, People's Republic of China.
Zhao XJ; Cancer Biology Research Center (Key Laboratory of the Ministry of Education), Tongji Medical College, Huazhong University of Science and Technology, Tongji Hospital, Wuhan, People's Republic of China.
Li F; Cancer Biology Research Center (Key Laboratory of the Ministry of Education), Tongji Medical College, Huazhong University of Science and Technology, Tongji Hospital, Wuhan, People's Republic of China.
Yuan Y; Cancer Biology Research Center (Key Laboratory of the Ministry of Education), Tongji Medical College, Huazhong University of Science and Technology, Tongji Hospital, Wuhan, People's Republic of China.
Yan DM; Cancer Biology Research Center (Key Laboratory of the Ministry of Education), Tongji Medical College, Huazhong University of Science and Technology, Tongji Hospital, Wuhan, People's Republic of China.
Cao H; Cancer Biology Research Center (Key Laboratory of the Ministry of Education), Tongji Medical College, Huazhong University of Science and Technology, Tongji Hospital, Wuhan, People's Republic of China.
Huang XY; Cancer Biology Research Center (Key Laboratory of the Ministry of Education), Tongji Medical College, Huazhong University of Science and Technology, Tongji Hospital, Wuhan, People's Republic of China.
Hu Z; Department of Obstetrics and Gynecology, Precision Medicine Institute, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, People's Republic of China.
Ma D; Cancer Biology Research Center (Key Laboratory of the Ministry of Education), Tongji Medical College, Huazhong University of Science and Technology, Tongji Hospital, Wuhan, People's Republic of China.
Gao QL; Cancer Biology Research Center (Key Laboratory of the Ministry of Education), Tongji Medical College, Huazhong University of Science and Technology, Tongji Hospital, Wuhan, People's Republic of China.; Pokaż więcej
Źródło :: Human gene therapy [Hum Gene Ther] 2020 Mar; Vol. 31 (5-6), pp. 325-338. Date of Electronic Publication: 2020 Mar 03.
Typ publikacji :: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :: BH3 Interacting Domain Death Agonist Protein/*genetics
Bcl-2-Like Protein 11/*genetics
Cisplatin/*pharmacology
Mitochondria/*metabolism
Ovarian Neoplasms/*genetics
Ovarian Neoplasms/*therapy
Adenoviridae/genetics ; Adenoviridae/metabolism ; Animals ; Antineoplastic Agents/pharmacology ; Apoptosis/drug effects ; BH3 Interacting Domain Death Agonist Protein/metabolism ; Bcl-2-Like Protein 11/metabolism ; Caspase 3/metabolism ; Cell Line ; Cell Proliferation/drug effects ; Drug Synergism ; Female ; Genetic Therapy ; Genetic Vectors/therapeutic use ; HEK293 Cells ; Humans ; Mice ; Mice, Inbred BALB C ; Mitochondria/genetics ; Tumor Cells, Cultured
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 20 20.

Tytuł :: Menadione-induced apoptosis in U937 cells involves Bid cleavage and stefin B degradation.
Autorzy :: Božič J; Department of Biochemistry and Molecular and Structural Biology, Jožef Stefan Institute, Ljubljana, Slovenia.; Jožef Stefan International Postgraduate School, Ljubljana, Slovenia.
Bidovec K; Department of Biochemistry and Molecular and Structural Biology, Jožef Stefan Institute, Ljubljana, Slovenia.; Jožef Stefan International Postgraduate School, Ljubljana, Slovenia.
Vizovišek M; Department of Biochemistry and Molecular and Structural Biology, Jožef Stefan Institute, Ljubljana, Slovenia.
Dolenc I; Department of Biochemistry and Molecular and Structural Biology, Jožef Stefan Institute, Ljubljana, Slovenia.
Stoka V; Department of Biochemistry and Molecular and Structural Biology, Jožef Stefan Institute, Ljubljana, Slovenia.; Jožef Stefan International Postgraduate School, Ljubljana, Slovenia.; Pokaż więcej
Źródło :: Journal of cellular biochemistry [J Cell Biochem] 2019 Jun; Vol. 120 (6), pp. 10662-10669. Date of Electronic Publication: 2019 Jan 16.
Typ publikacji :: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :: Gene Expression Regulation, Neoplastic*
Antineoplastic Agents/*pharmacology
Apoptosis/*drug effects
BH3 Interacting Domain Death Agonist Protein/*genetics
Cystatin B/*genetics
Lysosomes/*drug effects
Vitamin K 3/*pharmacology
Amino Acid Chloromethyl Ketones/pharmacology ; Apoptosis/genetics ; Apoptosomes/drug effects ; Apoptosomes/metabolism ; BH3 Interacting Domain Death Agonist Protein/metabolism ; Caspase 3/genetics ; Caspase 3/metabolism ; Caspase 9/genetics ; Caspase 9/metabolism ; Cathepsin B/antagonists & inhibitors ; Cathepsin B/genetics ; Cathepsin B/metabolism ; Cathepsin C/antagonists & inhibitors ; Cathepsin C/genetics ; Cathepsin C/metabolism ; Cathepsin D/antagonists & inhibitors ; Cathepsin D/genetics ; Cathepsin D/metabolism ; Cathepsins/antagonists & inhibitors ; Cathepsins/genetics ; Cathepsins/metabolism ; Cystatin B/metabolism ; Humans ; Leucine/analogs & derivatives ; Leucine/pharmacology ; Lysosomes/metabolism ; Membrane Potential, Mitochondrial/drug effects ; Mitochondria/drug effects ; Mitochondria/metabolism ; Pepstatins/pharmacology ; Poly(ADP-ribose) Polymerases/genetics ; Poly(ADP-ribose) Polymerases/metabolism ; Protease Inhibitors/pharmacology ; Proteolysis/drug effects ; Signal Transduction ; U937 Cells
: Czasopismo naukowe

Szczegóły

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